DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and kcnk5

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_017945689.1	Gene:	kcnk5 / 100489489	XenbaseID:	XB-GENE-979847	Length:	478	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	99/349 - (28%)
Similarity:	155/349 - (44%)	Gaps:	50/349 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LLVSLSIYCGVGGLIFRHLERP-----AEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDELLS 127
            |..::..|..:|..||:.||.|     .::.:.:.:|.:.|       |:.|.   ..:|:|:|.
Frog     8 LTSAVIFYLSIGAAIFQVLEEPNWKAATQLYKENKVKILAK-------HSCLT---PRDLEEILE 62

  Fly   128 FELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFC 192
                    .|..||..|:.|..:..|    ..|:...||.|::||:||||||||.|.|:.||:||
Frog    63 --------TVSSAAGQGVTITGNTTF----NNWNWPNAVIFAATVITTIGYGNIAPKTSAGRLFC 115

  Fly   193 ICFALIGIPFTLTVIADWGRLFATAVSVFGKHMPTKPKFTNFIGKTWFYAILAVGFLGVYLAAGA 257
            |.:.|.|:|..||.|:..|:.|.......|:.: ||...|....:....||..:..:.|:|.. .
Frog   116 IFYGLFGVPLCLTWISALGKFFGGRAKRLGQFL-TKRGVTLRKAQITCTAIFIIWGVLVHLVI-P 178

  Fly   258 GLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVP---KKPNYMLL----CTLYILIGLALTSTIIE 315
            ..:.:..:.|.:.:|.||.|||:|||||||.|.   .|.||.:|    ..::|.:|||..|..:
Frog   179 PFIFMKTEGWDYIEGLYFSFITITTIGFGDYVAGVNPKVNYNVLYRYFVEIWIYLGLAWLSLFV- 242

  Fly   316 LVRRQYATSWAKLQELSGPMAETLRRLGETAGTGLDYTALQKVLTVSMPKWNSKKNEHSPDIAAL 380
                    :|.....|....|...||.........|....|   |.::|..|.|.......::..
Frog   243 --------NWKVSMFLEVHKAIKKRRKRRKESFENDPQMKQ---TKAVPMTNPKDVNIFSFLSKK 296

  Fly   381 EAITNAILKEVKE--AQNNKPKVL 402
            |...|.::|::.:  .:|:..|:|
Frog   297 EETYNDLIKQIGKNGLKNSHEKIL 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	28/56 (50%)
		Ion_trans	<240..314	CDD:278921	28/80 (35%)
		Ion_trans_2	<266..319	CDD:285168	24/59 (41%)
kcnk5	XP_017945689.1	Ion_trans_2	<82..137	CDD:369572	28/54 (52%)
kcnk5	XP_017945689.1	Ion_trans_2	165..243	CDD:369572	27/87 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9679
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000