DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and kcnk15

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_005161945.1	Gene:	kcnk15 / 100000132	ZFINID:	ZDB-GENE-080220-30	Length:	357	Species:	Danio rerio

Alignment Length:	284	Identity:	81/284 - (28%)
Similarity:	121/284 - (42%)	Gaps:	58/284 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDE 124
            |..:..:.|::.:..|..||..:|..||...|            :.|:|.|..  ...|:.....
Zfish     3 KQNVRTLSLILCIFSYLLVGAAVFVALESDTE------------SARKRMLEH--KRAELRRKYR 53

  Fly   125 LLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYE---RWSILQAVFFSSTVLTTIGYGNIVPVTT 186
            ....:..:.|..::||              ||:.   :|....:.:|:.||:||||||:..|.|.
Zfish    54 FTDGDYQELERVLRQA--------------EPHRAGTQWRFAGSFYFAITVITTIGYGHAAPGTD 104

  Fly   187 GGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGKHMP-------TKPKFTNFIGKTWFYAIL 244
            .|::||:.:|.:|||.||.:....|....|.|......|.       |:....|.:
Zfish   105 AGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMKRALGLQRTEISTQNMV--------- 160

  Fly   245 AVGFLGVY--LAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLV--PKKPN------YMLLC 299
            .||.|...  |..||.....:| .||||..:|:||||:|||||||.|  .||.:      |:|..
Zfish   161 LVGVLSCLGTLCVGAAAFSHFE-SWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFS 224

  Fly   300 TLYILIGLALTSTIIELVRRQYAT 323
            .:|||:||.:....:.||..::.|
Zfish   225 FIYILLGLTVIGAFLNLVVLRFLT 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	22/59 (37%)
		Ion_trans	<240..314	CDD:278921	33/83 (40%)
		Ion_trans_2	<266..319	CDD:285168	28/60 (47%)
kcnk15	XP_005161945.1	Ion_trans_2	<77..132	CDD:285168	22/54 (41%)
kcnk15	XP_005161945.1	Ion_trans_2	167..243	CDD:285168	31/76 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910