Protein Alignment Sk1 and LCB5

DIOPT Version :9

• Sequence 1: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_013361.1
• Gene: LCB5 / 850964
• SGDID: S000004250
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 701
• Identity: 151/701 - (21%)
• Similarity: 266/701 - (37%)
• Gaps: 189/701 - (26%)

  Fly     2 TANTGTSGENLMGNGGKTHEP----------------------------------STPTSDTEVA 32
            |:.|.||.::|..| .|.|.|                                  |:|:|....:
Yeast   106 TSTTDTSKDDLSAN-PKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANSSPSSPLSSS 169

  Fly    33 SGTPTELSEIFFVDNSRRKQSIKIQVKLCPEGVYLRRETEEDDHI---NEQLIRIDDIIGSRYGR 94
            ....:|..::..:::|::|:.         :|..|.|.:.....:   .....::.::|.:|
Yeast   170 MSNISEKCDLDELESSQKKER---------KGNSLSRGSNSSSSLLTSRSPFTKLVEVIFAR--- 222

  Fly    95 RLKKRARGGLNSCRNPNVPGQEA---DSEPDSDNSAYLYIYAYLKKEKPLRRVQTLRILRFRSSN 156
                       ..|:..||.:.:   |.:|.|.        ::||:|..|
Yeast   223 -----------PRRHDVVPKRVSLYIDYKPHSS--------SHLKEEDDL--------------- 253

  Fly   157 DYGVNLQTAEMWHHTIRKHKRGNGSSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEV 221
                   ..|:...:.:..:|          .|.:.:::||..|.||.::||..:..|||..:..
Yeast   254 -------VEEILKRSYKNTRR----------NKSIFVIINPFGGKGKAKKLFMTKAKPLLLASRC 301

  Fly   222 QYDLQITTHPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIP 286
            ..::..|.:|.:|.|..|...  :.:|..|..|||||:.:||:|||.:|.|..:|...:.:..||
Yeast   302 SIEVVYTKYPGHAIEIAREMD--IDKYDTIACASGDGIPHEVINGLYQRPDHVKAFNNIAITEIP 364

  Fly   287 CGSGNGLAKSVAHHCNEPYEPKPILHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGL 351
            |||||.::.| .|..|.|      .::||..:....|.:|::.....:..:.....||||..:||
Yeast   365 CGSGNAMSVS-CHWTNNP------SYSTLCLIKSIETRIDLMCCSQPSYAREHPKLSFLSQTYGL 422

  Fly   352 IADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGI 416
            ||:.||.:|.:|.:|..||.|.....:|..:.|...: |:....|.:      .||.........
Yeast   423 IAETDINTEFIRWMGPARFELGVAFNIIQKKKYPCEI-YVKYAAKSK------NELKNHYLEHKN 480

  Fly   417 RSSLPLN----------------AGEFHDLPEEEEGEAVLDGEQFADAISLDRSVYRQHADSWHS 465
            :.||...                ..|:....|:|:.:|..|.|.       ...:.|..|||  |
Yeast   481 KGSLEFQHITMNKDNEDCDNYNYENEYETENEDEDEDADADDED-------SHLISRDLADS--S 536

  Fly   466 AMSRRTAYYSLGGP---SMRSNRSRM--SISQRIEAANAEFAERVPTGTIPPLQMPLLSSDGWIC 525
            |...:...:.:..|   .:.|:..|:  :||..:..        ..||.:|
Yeast   537 ADQIKEEDFKIKYPLDEGIPSDWERLDPNISNNLGI--------FYTGKMP-------------- 579

  Fly   526 EDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGED 590
                          ::::|..|.|.:...||.:.:||.....|..::...:|.|:.|:|:...|.
Yeast   580 --------------YVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSHVLQPEV 630

  Fly   591 PFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTSGQ 641
            ...|::   |::|.|...:|:..||||:....|:|.|:||.|...:..:|:
Yeast   631 LHSKIL---AYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGR 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	112/453 (25%)
		DAGK_cat	191..330	CDD:279163	45/138 (33%)
LCB5	NP_013361.1	LCB5	267..603	CDD:224513	97/406 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343284
Domainoid	1	1.000	90	1.000	Domainoid score	I1770
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I1088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		mtm9231
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	LDO	PTHR12358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R653
SonicParanoid	1	1.000	-	-		X918
TreeFam	1	0.960	-	-
	13	12.780