DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sk1 and SPAC4A8.07c

DIOPT Version :9

Sequence 1:	NP_572717.1	Gene:	Sk1 / 32089	FlyBaseID:	FBgn0030300	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_593818.1	Gene:	SPAC4A8.07c / 2543328	PomBaseID:	SPAC4A8.07c	Length:	458	Species:	Schizosaccharomyces pombe

Alignment Length:	451	Identity:	110/451 - (24%)
Similarity:	173/451 - (38%)	Gaps:	120/451 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 KQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLTRYSGIVV 253
            ::.::.:||..|.||.:.:::.:..|:.:.|....::.:|....:||...:...  :..|.||:.
pombe   106 RRFIVFINPHGGKGKAKHIWESEAEPVFSSAHSICEVVLTRRKDHAKSIAKNLD--VGSYDGILS 168

  Fly   254 ASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCNEPYEPKPILHATLTCM 318
            ..|||||:||:|||.||.|:..|.: ||:.:||.||||      |...|...:.||.|.| |..:
pombe   169 VGGDGLFHEVINGLGERDDYLEAFK-LPVCMIPGGSGN------AFSYNATGQLKPALTA-LEIL 225

  Fly   319 AGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRS 383
            .|:.|..|::..|    .|....||||:..:|:|||.||.:|..|.:|..|..|....||.
pombe   226 KGRPTSFDLMTFE----QKGKKAYSFLTANYGIIADCDIGTENWRFMGENRAYLGFFLRLF---- 282

  Fly   384 YKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVLDGEQFADA 448
                         ::|..:.:.|:                                       |.
pombe   283 -------------QKPDWKCSIEM---------------------------------------DV 295

  Fly   449 ISLDRSVYRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAERVPTGTIPPL 513
            :|.||:..:...:.     |:..|      |...|:.|..::|...|:....|
pombe   296 VSSDRTEIKHMYEK-----SKNLA------PMSESSDSDKTVSTSPESHLLTF------------ 337

  Fly   514 QMPLLSSDGWICEDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLN 578
                        |..|..:..|....:::.|....|.:..|||||.:||:.....|..||:....
pombe   338 ------------EINDLSIFCAGLLPYIAPDAKMFPAASNDDGLIDVVIVYSKQFRKSLLSMFTQ 390

  Fly   579 LNAG-----THLPIGEDPFIKVVPCRAFRIEP--SSSDGILVVDGERVEYGPIQAEVMPGL 632
            |:.|     .||     .:.||   |:||..|  :.......:|||.....|.:..|.|.|
pombe   391 LDNGGFYYSKHL-----NYYKV---RSFRFTPVNTGKRHYFALDGESYPLEPFECRVAPKL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	106/439 (24%)
Sk1	NP_572717.1	DAGK_cat	191..330	CDD:279163	45/138 (33%)
SPAC4A8.07c	NP_593818.1	LCB5	104..442	CDD:224513	108/448 (24%)
SPAC4A8.07c	NP_593818.1	DAGK_cat	107..236	CDD:279163	45/138 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I2510
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I1327
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		otm47232
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	LDO	PTHR12358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R653
SonicParanoid	1	1.000	-	-		X918
TreeFam	1	0.960	-	-
	12	11.850