Protein Alignment Sk1 and Sphk1

DIOPT Version :9

• Sequence 1: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017169887.1
• Gene: Sphk1 / 20698
• MGIID: 1316649
• Length: 512
• Species: Mus musculus
• Alignment Length: 463
• Identity: 142/463 - (30%)
• Similarity: 215/463 - (46%)
• Gaps: 120/463 - (25%)

  Fly   184 PADCGK-------QLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTR 241
            |.:|.:       ::|:||||:.|.||..:|||.:|.|.|.|||:.:.|.:|....:|:|.|...
Mouse   133 PVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHARELVCAE 197

  Fly   242 RDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCNEPYE 306
            .  |..:..:.|.|||||.:||:||||||.||..|.:: ||..:|.||||.||.||.|:..  ||
Mouse   198 E--LGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQK-PLCSLPGGSGNALAASVNHYAG--YE 257

  Fly   307 PKP----ILHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGA 367
            ...    :::.||.....:.:||:::.:..|:..:   :||.||:.||.:||:|:|||:.|.:|.
Mouse   258 QVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLR---LYSVLSLSWGFVADVDLESEKYRRLGE 319

  Fly   368 QRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPE 432
            .|||:....||..||.|:|:::||        ||         .|.|
Mouse   320 IRFTVGTFFRLASLRIYQGQLAYL--------PV---------GTVA------------------ 349

  Fly   433 EEEGEAVLDGEQFADAISLDRSVYRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAA 497
                                               |:|.|
Mouse   350 -----------------------------------SKRPA------------------------- 354

  Fly   498 NAEFAERVPTGT-IPPLQMPLLSSDGW-ICEDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYL 560
             :...::.|..| :.||:.|:.|.  | :..:.|||:|.....|||||::|.||..|.:.|:::|
Mouse   355 -STLVQKGPVDTHLVPLEEPVPSH--WTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHL 416

  Fly   561 VIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQ 625
            ..:|.||||..||...|.:..|.|:.: :.|::..||..|||:||.|..|:..||||.:....:|
Mouse   417 FYVRAGVSRAALLRLFLAMQKGKHMEL-DCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQ 480

  Fly   626 AEVMPGLI 633
            .:|.|..:
Mouse   481 GQVHPNYL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	137/445 (31%)
		DAGK_cat	191..330	CDD:279163	58/142 (41%)
Sphk1	XP_017169887.1	PLN02958	<141..474	CDD:215517	137/439 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836242
Domainoid	1	1.000	102	1.000	Domainoid score	I6809
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4295
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	LDO	PTHR12358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R653
SonicParanoid	1	1.000	-	-		X918
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.830