Protein Alignment Sk1 and sphk2

DIOPT Version :9

• Sequence 1: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_002938325.1
• Gene: sphk2 / 100494664
• XenbaseID: XB-GENE-991354
• Length: 592
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 206/638 - (32%)
• Similarity: 309/638 - (48%)
• Gaps: 124/638 - (19%)

  Fly    52 QSIKIQVKLCPEGVYLRR--ETEEDDHINEQLIRIDDIIGSRYGRRLKKRARGGLNSCRNPNVPG 114
            :.|:..:.|...|::::|  ...||||  ..::.:.|::|....|
 Frog    21 KGIRYALSLTHTGLHIQRLVPKPEDDH--RLVLPLSDMVGCHTLR-------------------- 63

  Fly   115 QEADSEPDSDNSAYLYIYAY-LKKEK----PLR-RVQTLRILRFRSSNDYGVNLQTAEMWHHTIR 173
                |....|..||..||:| |||:|    |.| |.:.:|..|....::|..||..||.|...|:
 Frog    64 ----SHSSGDMFAYFSIYSYPLKKKKVTMGPSRTRQRLVRTFRVDEESEYNRNLAIAEKWATAIK 124

  Fly   174 --KHKRGNGSSS-------PADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITT 229
              ..:...||.:       |..  ::|::|:||..|.|...:..|..:.|:|||||:.|:|..|.
 Frog   125 CLIQEIPIGSETEFVPELLPRT--RRLMLLVNPCGGRGNALQQCQSHILPMLTEAEISYNLIQTE 187

  Fly   230 HPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLA 294
            ...:|:|.|:...  |.::.||:|.|||||.|||:||||||.||..|.: :|:||:||||||.||
 Frog   188 RQNHARELVQGIS--LEQWDGIIVISGDGLLYEVINGLMERPDWEDAIK-MPVGILPCGSGNALA 249

  Fly   295 KSVAHHC--NEPYEPKPILHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDI 357
            .::.::.  ::....:.:|:..|....|...|||:|.:...:..:.|   |||||.||.|:|:||
 Frog   250 GAINYNAGFDQAMGSELLLNCILLLCRGTVIPMDLVSLTTCSGIRSF---SFLSVAWGFISDVDI 311

  Fly   358 ESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPL 422
            |||:.|.:|:.|||:..:.|:..||:|:||:|||       |.::|.|.:....|.:...|..|.
 Frog   312 ESEKYRHMGSARFTVGTMVRVASLRTYRGRLSYL-------PVLDAHRPICRSITLSPNGSLAPF 369

  Fly   423 NAGEFH--------------------------DLPEEE----EGEAVLDGEQF-ADAISLDRSVY 456
            ...:.|                          :||..|    .....|....| .|::|.|.|
 Frog   370 QRSQLHRTISDIGLCEERNVMYKRSSTALDTNELPSFESPSPSSPTALHSSSFNFDSLSDDPS-- 432

  Fly   457 RQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAERVPTGTIPPLQMPLLSSD 521
              :.||.:|...:...::.:.||.                          ...:|.|..||  ..
 Frog   433 --YQDSVYSKDLKPQRHHQVNGPK--------------------------DDLLPSLGQPL--PK 467

  Fly   522 GWICEDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLP 586
            .||..:.:||:|.|.|.:||.:|:|.||.|..|||||:|..::.|:||..|:...|.:..|||..
 Frog   468 NWIIVEDNFVLVLAIYQSHLGADLFTAPFSTFDDGLIHLFFVKAGISRAALVRLFLAMEKGTHFE 532

  Fly   587 IGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTS 639
            . |.|::..:|.||||:||.:..||:.|||||||||||||::..||.|::|.|
 Frog   533 T-ECPYLTHIPVRAFRLEPLTRKGIITVDGERVEYGPIQAQIHKGLSNLITGS 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	158/465 (34%)
		DAGK_cat	191..330	CDD:279163	58/140 (41%)
sphk2	XP_002938325.1	PLN02958	<143..562	CDD:215517	154/466 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3683
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32456
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2769
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		mtm9501
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X918
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060