DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Evi5 and PAM1

DIOPT Version :9

Sequence 1:	NP_727526.2	Gene:	Evi5 / 32088	FlyBaseID:	FBgn0262740	Length:	807	Species:	Drosophila melanogaster
Sequence 2:	NP_197097.1	Gene:	PAM1 / 831450	AraportID:	AT5G15930	Length:	356	Species:	Arabidopsis thaliana

Alignment Length:	344	Identity:	124/344 - (36%)
Similarity:	196/344 - (56%)	Gaps:	29/344 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LNSLHSTHSRKNSDTSQISLTSSGNSVAEEDIWTTWATIL----NDWEGALKRKNPCVSELVRRG 116
            |...|.:..::.:.|.     ||.|...||...|.|..::    :||:..::||...|...:|:|
plant    26 LKQEHGSSPQRFTKTK-----SSINYEKEEKRVTKWRKMIGTGGSDWKHYVRRKPHVVKRRIRKG 85

  Fly   117 IPHHFRAIVWQQLSGASD------GDKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPG 175
            ||...|.:|||.:||:.|      |...|...|  .|||.|..|.|||:||:|...||:::.|||
plant    86 IPDCLRGLVWQLISGSRDLLLMNPGVYVQLVIY--ETSASELDIIRDISRTFPSHVFFQKRHGPG 148

  Fly   176 QEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQ---QHRMRHMFKPSMS 237
            |.:|:||:||||::||:|||.||.|||.||||:.|.||:||.:||.:::   ...:..:::..:.
plant   149 QRSLYNVLKAYSVYDRDVGYVQGMGFIAGLLLLYMSEEDAFWLLVALLKGAVHSPIEGLYQAGLP 213

  Fly   238 ELGLCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGME 302
            .:...:.|.:.||:|.:|.:..||.|:....:||||.||:|:::.:|..:.:.||.||||:||::
plant   214 LVQQYLLQFDQLVRELMPKLGEHFTQEMINPSMYASQWFITVFSYSLPFHSALRIWDVFLAEGVK 278

  Fly   303 FIFKVALALLLTGKDTLLCLDMEAM---LKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKME 364
            .:|||.||||....|.||.|..|.:   |:.|.::     ..|.:....||||||: :||:::|:
plant   279 IVFKVGLALLKHCHDDLLKLPFEELMHALRNFPED-----AMDPDTLLPLAYSIKV-SKRLEEMK 337

  Fly   365 KEYQDLKKKEQEEMAELRR 383
            ::......|..:....:|:
plant   338 QDCDKAVAKPTQTAKSVRQ 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Evi5	NP_727526.2	TBC	113..320	CDD:214540	91/215 (42%)
Evi5	NP_727526.2	DUF4527	627..>731	CDD:291689
PAM1	NP_197097.1	TBC	82..296	CDD:214540	91/215 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	168	1.000	Domainoid score	I1178
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H121902
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1084
orthoMCL	1	0.900	-	-		OOG6_101755
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.770