Protein Alignment Evi5 and evi5b

DIOPT Version :10

• Sequence 1: NP_727526.2
• Gene: Evi5 / 32088
• FlyBaseID: FBgn0262740
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_009300706.3
• Gene: evi5b / 553306
• ZFINID: ZDB-GENE-041111-244
• Length: 837
• Species: Danio rerio
• Alignment Length: 772
• Identity: 350/772 - (45%)
• Similarity: 507/772 - (65%)
• Gaps: 58/772 - (7%)

  Fly     6 TTTASSAESQAKMDVKGGALPGEENLPTSEMDLLAKLEAANKLIESDAKSLNSLHSTHSRKNSDT 70
            ||.|||.   |.:.....|.|.:  |...:::||||||..|:|:|:|:|||.|::.  ||:||.:
Zfish    41 TTVASST---ASLSSPSSASPTQ--LSPDDVELLAKLEEQNRLLETDSKSLRSVNG--SRRNSGS 98

  Fly    71 SQISLTSSGNSVA--EEDIWTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSGAS 133
            |.:|.:|:.::::  |||.|..|..|:|:||...|:|...:.||||:|:||||||||||.|..|.
Zfish    99 SLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQLKELVRKGVPHHFRAIVWQLLCNAQ 163

  Fly   134 D-GDKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQ 197
            : ..|:||:|.:|.||.|||:|||||||||||.|||||||..|||.||||:|||||.||||||||
Zfish   164 NLPIKEQYSELLKMTSPCEKLIRRDIARTYPEHEFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQ 228

  Fly   198 GSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQ 262
            ||.||||||||||||||||.|.|::||::|:|.:|||||:||||||||.|.::|||:|::|:|||
Zfish   229 GSAFIVGLLLMQMPEEEAFCVFVKLMQEYRLRELFKPSMAELGLCMYQFECMIQEQLPELHVHFQ 293

  Fly   263 QQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAM 327
            .|.|.|:|||||||||::.|:..:.::.||.|:|:.||:|.:|:|.:|:|...:..|:.||||.|
Zfish   294 AQSFHTSMYASSWFLTIFLTSFPLPVATRIFDIFMCEGLEIVFRVGMAILQMNQAELMQLDMEGM 358

  Fly   328 LKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLK 392
            |:.|||.:|.::::..:.....||.:|.|.|:|||:||||..:|.||.||..|::|||.||.|||
Zfish   359 LQHFQKVIPHQLDSGPDKVIQAAYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLK 423

  Fly   393 QRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLR 457
            ||.:.||.|||.|||||::|||:||:|.|.:|.::.||..:::...|.|.|||.|...:|    :
Zfish   424 QRIDTLEKESASLADRLIQGQVTRAQEAEENYLVKRELATVKQHIEETSVQLEQAQSTIR----Q 484

  Fly   458 LQENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEE 522
            ||:   .....|.|.:        ||::.|       |..|||:.|...|||:..::.::.|:..
Zfish   485 LQQ---PFAKGNPRYT--------EESILQ-------LERELVQARLKEAESQCALKEMQDKILY 531

  Fly   523 LEEDKKTLRETTPD-NSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSES 586
            :|:...:|    || |:|..||:|||..|||||||...||:|:|:|::|...|||.||
Zfish   532 MEQRNTSL----PDENNVVRLQEELIGVKLREAEALTGLKELRQQVRDLEEHWQRHLA------- 585

  Fly   587 ERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQV 651
             ||......:|:|        :.:||    |::|||:.|:||.|...||:|.|.:::|||||.|:
Zfish   586 -RTAGRWKDSPRK--------NAASE----LQDELMSVRLREAEAQAELRETRQRMLELETQNQI 637

  Fly   652 STNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTV 716
            .:|||||.:.|.:.|::.|.:...:.|.:.::.:|.:.:.:::|.:.|:|:|.|:::..:....:
Zfish   638 HSNQLRRAELEARNLQDRLHVLSNQNKMLHSELQETKRKQAEIECKNKEEVMAVRLREADNIAAM 702

  Fly   717 AELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQDRLADMKAELTALKSRGKFP 773
            |||:|:||.||.:..|...:|:|. |.|.|..:|||:|::||:|.|:..|:.....|
Zfish   703 AELQQQISELEIQKEEGKVQGQLN-NTDSSQYIRDLKDQIADLKHEIRCLRGHQGLP 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Evi5	NP_727526.2	TBC	113..320	CDD:214540	133/207 (64%)
		Smc	<358..>761	CDD:440809	155/403 (38%)
evi5b	XP_009300706.3	None