Protein Alignment Evi5 and tbc1d4

DIOPT Version :9

• Sequence 1: NP_727526.2
• Gene: Evi5 / 32088
• FlyBaseID: FBgn0262740
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_005167832.1
• Gene: tbc1d4 / 321065
• ZFINID: ZDB-GENE-030131-9881
• Length: 1247
• Species: Danio rerio
• Alignment Length: 584
• Identity: 139/584 - (23%)
• Similarity: 252/584 - (43%)
• Gaps: 137/584 - (23%)

  Fly    12 AESQAKMDVKGGALP-----GEENLPTS----------EMDLLAKLEAANKLIESDAKSLNSLHS 61
            |.:|.:.|..|...|     |::..|..          :..||.::|..|:.:|..::.     .
Zfish   759 ALTQDQGDQTGPQSPEQSSAGQKRSPADYRGLWKKAIHQQILLIRMEKENQRLEEASRD-----E 818

  Fly    62 THSRK-NSDTSQISLTSSGNSVAEEDIWTTWATILNDWEGALKRKNPC----------VSELVRR 115
            .|.|| ..|..::...|       :::...|..         |..:||          :...|.:
Zfish   819 LHIRKMKLDYQEVCSCS-------KELQALWDR---------KLSSPCRTKVQWNKEEIHSAVCQ 867

  Fly   116 GIPHHFRAIVW----------QQLSGASDGDKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKE 170
            |:|...|..||          |:|.......:..:.:.:|..:|.:..|..|:.||:|..::|..
Zfish   868 GVPKSRRGEVWLLLSQQHRLRQRLPHRQQPPETPFQDLLKQLTAQQHAILVDLGRTFPTHQYFSA 932

  Fly   171 KDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPS 235
            :.|.||.:|:|::|||||.|.|||||||..|:.||||:.|.||::|..|..:|....:|..::|.
Zfish   933 QLGAGQLSLYNLLKAYSLLDTEVGYCQGISFVAGLLLLHMSEEQSFDTLKFLMYDLGIRRQYRPD 997

  Fly   236 MSELGLCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEG 300
            |..|.:.||||..|:.:...:::.|..:.....::||:.|||||:.:...:....||.|:...:|
Zfish   998 MISLQIQMYQLSRLLHDYHRNLYSHLDEHEICPSLYAAPWFLTLFASQFPLGFVARIFDLLFVQG 1062

  Fly   301 MEFIFKVALALLLTGKDTLL-CLDMEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKME 364
            .|.||||||.||.:.:..:| |...|:::.:.:..:|....:.:|.....|..:.: :|:::..|
Zfish  1063 TEVIFKVALCLLSSHEGEILECDSFESIVDYLKSTIPTLTHSQMEEIITKAIEMDI-SKQLQAYE 1126

  Fly   365 KEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTE 429
            .||..|    |:|:::...|                  :|.:|||     .:.|:..|
Zfish  1127 VEYHVL----QDELSDAPPL------------------SEDSDRL-----DKLEKANT------- 1157

  Fly   430 LMQLRRSYLEVSHQLENANEEVRGLSLRLQENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSC 494
              |||:..:::..:|:.|.       |::|....|::|..||:|.:..|
Zfish  1158 --QLRKQNMDLLEKLQAAR-------LKIQTLESSVESFLSRESKMKHL---------------- 1197

  Fly   495 LLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQ-DELIASKLREAEAS 557
                              ||:|:.:....::..:.:|.:.|.::.|.:: .:|.:|...:|:|:
Zfish  1198 ------------------IRSLEQEKASYQKTIERMRNSLPSDTTAEVEMTQLKSSTNGKAKAA 1243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Evi5	NP_727526.2	TBC	113..320	CDD:214540	75/216 (35%)
		DUF4527	627..>731	CDD:291689
tbc1d4	XP_005167832.1	PTB	16..159	CDD:214675
		PTB_TBC1D1_like	161..415	CDD:269967
		DUF3350	756..812	CDD:288663	11/52 (21%)
		TBC	867..1082	CDD:214540	74/214 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810