Protein Alignment Evi5 and evi5a

DIOPT Version :9

• Sequence 1: NP_727526.2
• Gene: Evi5 / 32088
• FlyBaseID: FBgn0262740
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_009296272.1
• Gene: evi5a / 100332570
• ZFINID: ZDB-GENE-110218-2
• Length: 607
• Species: Danio rerio
• Alignment Length: 747
• Identity: 232/747 - (31%)
• Similarity: 374/747 - (50%)
• Gaps: 152/747 - (20%)

  Fly     8 TASSAESQAKMDVKGGALPGEENLPTSEMDLLAKLEAANKLIESDAKSLNSLHSTHSRKNSDTSQ 72
            |.||..|          .||.| |.|.||.||||||..|:|:|:|:|||.|::.. .|..:....
Zfish     5 TVSSLSS----------TPGSE-LSTDEMKLLAKLEEQNRLLETDSKSLYSVNGV-LRNPTSPKT 57

  Fly    73 ISLTSSGNSVAEEDIWTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSGASD-GD 136
            .||        ||:|   |..::|:||...|||...:..|.|||:|.|.||:|||.|..:.: ..
Zfish    58 FSL--------EENI---WENVINEWEDWSKRKVGQIKVLTRRGVPAHLRAMVWQLLCDSGNVSV 111

  Fly   137 KKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSGF 201
            :.||::.:|::|..|.:|.||:.||:|..:.|.......:|.||||:||||:.|:|:|||:||.|
Zfish   112 RPQYSDLLKSSSPSETLIHRDLTRTFPHHQLFHNHQSISKETLFNVLKAYSVLDQEIGYCKGSVF 176

  Fly   202 IVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQQGF 266
            ||||||.||.|||||.|.|::|:..|||.::|.|..|||.|:||.:::::||:|::|.|||.|||
Zfish   177 IVGLLLTQMAEEEAFCVFVRLMKDFRMRELYKSSRDELGCCIYQFDSMIKEQLPELHSHFQTQGF 241

  Fly   267 QTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAMLKFF 331
            ||::::||||.:::.::|.::.:.||.|:|:.||:|.:|:|.||:|...:..|:.||.|.|:|..
Zfish   242 QTSVFSSSWFYSIFLSSLPISAAMRIFDIFMCEGLEIVFRVGLAVLDMKQTELIKLDNEGMMKCL 306

  Fly   332 QKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNE 396
            |.........|:  ....||.||.|..:||:..|:|:.:|.||.||..||:.|..||..||.|..
Zfish   307 QNLESWESNPDL--MIEAAYQIKYNGSQMKQFRKDYEAIKAKELEEQEELKGLCSENKHLKHRLA 369

  Fly   397 LLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQEN 461
            :||...:|
Zfish   370 ILERRCSE--------------------------------------------------------- 377

  Fly   462 NVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEED 526
                                        ::||.|.:||.|.:..:|.|::.::.::|...:|||
Zfish   378 ----------------------------KLVSQLRKELEKTQLNIASSQNALKEMQANTSQLEE- 413

  Fly   527 KKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTN 591
               :.....::||.:|:.|||:.:||||||...||.||..::::..:.|:.|...|:
Zfish   414 ---ISAAPDEHSVLYLRTELISCRLREAEALTELKQLKNHIKDMDEKLQQVLCGGQQ-------- 467

  Fly   592 AVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQL 656
            .|.||                 ...|:.||::||::|..|...|||.|..:|:|:||.::..|||
Zfish   468 RVSST-----------------QNDLQVELLSTRLKETLTQAILKESRHALMQLQTQNEIHRNQL 515

  Fly   657 RRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQ 721
            :|.:......::.|:...:..||:.::.::.:..:..::::.|..      :..:....:..|::
Zfish   516 KRTEAHVSSQRDHLQELTSHNKDLHSQLQQIRCHFLAVQNKWKGN------EDGDAGNLIERLQK 574

  Fly   722 EISRLE------TKNSEMLAEGELRANLDDSD 747
            :|:.|:      :|.:....:....|:|:..|
Zfish   575 QITELQIQIQTFSKCAPSSCQPSTSASLEHKD 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Evi5	NP_727526.2	TBC	113..320	CDD:214540	96/207 (46%)
		DUF4527	627..>731	CDD:291689	22/109 (20%)
evi5a	XP_009296272.1	TBC	87..295	CDD:214540	96/207 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191811at2759
OrthoFinder	1	1.000	-	-		FOG0000497
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101755
Panther	1	1.100	-	-	O	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1412
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.920