DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gs2 and GLN1

DIOPT Version :9

Sequence 1:	NP_001285121.1	Gene:	Gs2 / 32087	FlyBaseID:	FBgn0001145	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_015360.2	Gene:	GLN1 / 856147	SGDID:	S000006239	Length:	370	Species:	Saccharomyces cerevisiae

Alignment Length:	359	Identity:	218/359 - (60%)
Similarity:	257/359 - (71%)	Gaps:	13/359 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ARINKT-ILDRYLSLPLQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSCYQ 79
            |.|.|| ||.:||.|..:..|: |.|||||||| :||.|.|||.....|..:||.||:||||..|
Yeast     4 ASIEKTQILQKYLELDQRGRII-AEYVWIDGTG-NLRSKGRTLKKRITSIDQLPEWNFDGSSTNQ 66

  Fly    80 AEGSNSDTYLYPVAIYKDPFRRGNNILVMCDTYKFDGTPTDTNKRKTCLEVANKCAA---EEPWF 141
            |.|.:||.||.|||.|.||||||:||:|:...|..||||...|.|.   |.|...||   ||.||
Yeast    67 APGHDSDIYLKPVAYYPDPFRRGDNIVVLAACYNNDGTPNKFNHRH---EAAKLFAAHKDEEIWF 128

  Fly   142 GIEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAE 206
            |:|||||..|......||||.|:|.|||||||||||.||||||:::||||||||||:::||.|||
Yeast   129 GLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAE 193

  Fly   207 VMPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAM 271
            |||:|||||||||.||.:||.|||||:.|||::|||||..:..|||:.|||||||.|||||||.|
Yeast   194 VMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEM 258

  Fly   272 REDGGIRDIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIP 336
            |:.||::.||:|:.||||.|..||:.|    |.||..||||:|||:|:..||:||||||.|||||
Yeast   259 RQPGGMKYIEQAIEKLSKRHAEHIKLY----GSDNDMRLTGRHETASMTAFSSGVANRGSSIRIP 319

  Fly   337 RGVNDDGKGYFEDRRPSSNCDPYSVVEAILRTIC 370
            |.|..:|.||||||||:||.|||.|...:..|:|
Yeast   320 RSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVC 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gs2	NP_001285121.1	PLN02284	27..372	CDD:177922	211/347 (61%)
GLN1	NP_015360.2	PLN02284	19..352	CDD:177922	207/341 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344699
Domainoid	1	1.000	118	1.000	Domainoid score	I1281
eggNOG	1	0.900	-	-		E1_COG0174
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	433	1.000	Inparanoid score	I271
Isobase	1	0.950	-	0	Normalized mean entropy	S399
OMA	1	1.010	-	-		QHG63024
OrthoFinder	1	1.000	-	-		FOG0000848
OrthoInspector	1	1.000	-	-		otm46897
orthoMCL	1	0.900	-	-		OOG6_100668
Panther	1	1.100	-	-	LDO	PTHR20852
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R493
SonicParanoid	1	1.000	-	-		X534
TreeFam	1	0.960	-	-
	15	14.740