DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gs2 and Lgsn

DIOPT Version :9

Sequence 1:	NP_001285121.1	Gene:	Gs2 / 32087	FlyBaseID:	FBgn0001145	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_705829.1	Gene:	Lgsn / 266744	MGIID:	2672844	Length:	563	Species:	Mus musculus

Alignment Length:	391	Identity:	73/391 - (18%)
Similarity:	138/391 - (35%)	Gaps:	115/391 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LDRYLSLP---LQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSCYQAEGSN 84
            :.|..|:|   .||.::...::           ....|:.:| :||:..| |:..::|:     |
Mouse   152 VSRSKSIPAQFFQEKVIHGVFM-----------PRGYLELMP-NPKDNEV-NHIRATCF-----N 198

  Fly    85 SDTYLYPVAIYKDPFR----RGNNILVMCDTYKFDGTPTDTNKRKTC------LEVANKCAA--- 136
            ||..|.|..   ..||    ......|:|||:...|.|..|:.|...      |:.|..|..
Mouse   199 SDIVLMPEL---STFRVLPWAERTARVICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFCLLSAF 260

  Fly   137 --EEPWFGIEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIK 199
              :...||:.:.     .:...:.:|.:....         ..::.:.:::|:..|:    .|..
Mouse   261 IYDFCIFGVPEV-----INSKTISFPASTLLS---------NHDQPFMQELVEGLYQ----TGAN 307

  Fly   200 VSGTNAEVMPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNG----- 259
            |...::...|.|.|....|..|||..|:.:..|..|..::..:..:::|..:  .|..|.
Mouse   308 VESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGLQEVARRYNYIASLVIE--TGFCNSGILSH 370

  Fly   260 ----AGAHTNVSTKAMREDGGIRDI----EKAVAKLSK--------------CHERHIRAYDPKQ 302
                .|..||:....    .|:..:    :|.:|.|.|              |.:|:.:  |.:.
Mouse   371 SIWDVGGKTNMFCSG----SGVERLTLTGKKWLAGLLKHSAALSCLMAPAVNCRKRYCK--DSRD 429

  Fly   303 GQDNARRLTGKHETSSINDFSAGVANRGCSIRI----PRGVNDDGKGYFEDRRPSSNCDPYSVVE 363
            .:|:.....|.::.|             |::.|    .:|..      .|::..|:..:||.|:.
Mouse   430 LKDSVPTTWGYNDNS-------------CALNIKCHGEKGTQ------IENKLGSATANPYLVLA 475

  Fly   364 A 364
            |
Mouse   476 A 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gs2	NP_001285121.1	PLN02284	27..372	CDD:177922	72/387 (19%)
Lgsn	NP_705829.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..115
		GlnA	130..547	CDD:223252	73/391 (19%)
		Gln-synt_N	140..225	CDD:281884	20/93 (22%)
		Gln-synt_C	237..561	CDD:278546	47/285 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0174
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810