DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gs2 and glula

DIOPT Version :9

Sequence 1:	NP_001285121.1	Gene:	Gs2 / 32087	FlyBaseID:	FBgn0001145	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_853537.1	Gene:	glula / 100000775	ZFINID:	ZDB-GENE-030131-688	Length:	371	Species:	Danio rerio

Alignment Length:	361	Identity:	235/361 - (65%)
Similarity:	288/361 - (79%)	Gaps:	1/361 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SPNARINKTILDRYLSLPLQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSC 77
            |.:::::|.:..:|:.|| |.:.|||.|:|||||||.||||.||||..|:|.::||.||:||||.
Zfish     4 SASSQLSKVVKQQYMELP-QGDQVQAMYIWIDGTGEGLRCKTRTLDSEPKSIEDLPEWNFDGSST 67

  Fly    78 YQAEGSNSDTYLYPVAIYKDPFRRGNNILVMCDTYKFDGTPTDTNKRKTCLEVANKCAAEEPWFG 142
            |||||||||.||.|.|:::||||:..|.||:|:..|::....:||.|.||.::......:.||||
Zfish    68 YQAEGSNSDMYLIPAAMFRDPFRKDPNKLVLCEVVKYNRKTAETNHRHTCKKIMEMVGHQSPWFG 132

  Fly   143 IEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAEV 207
            :|||||.|..||||.|||.||||||||||||||||:|.|.||||:||||||||||:.:.||||||
Zfish   133 MEQEYTILGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVMICGTNAEV 197

  Fly   208 MPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAMR 272
            |||||||||||||||.:||.||:|||:|||:.|:||:|::.||||:||:|||||.|||.|||.||
Zfish   198 MPAQWEFQVGPCEGIDMGDHLWVARFILHRVCEDFGVVASFDPKPIPGNWNGAGCHTNFSTKEMR 262

  Fly   273 EDGGIRDIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIPR 337
            ||||::.||:.:.||.|.|..|||.||||.|.||||||||.||||:|::|||||||||.||||||
Zfish   263 EDGGLKCIEECIEKLGKRHNYHIRTYDPKGGLDNARRLTGHHETSNIHEFSAGVANRGASIRIPR 327

  Fly   338 GVNDDGKGYFEDRRPSSNCDPYSVVEAILRTICLDE 373
            .|..:.||||||||||:|||||:|.||::||..|||
Zfish   328 AVGQEKKGYFEDRRPSANCDPYAVTEALIRTCLLDE 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gs2	NP_001285121.1	PLN02284	27..372	CDD:177922	229/344 (67%)
glula	NP_853537.1	PLN02284	22..362	CDD:177922	227/339 (67%)
		Gln-synt_N	30..104	CDD:281884	47/73 (64%)
		Gln-synt_C	128..>356	CDD:278546	168/227 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593401
Domainoid	1	1.000	156	1.000	Domainoid score	I4143
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134752
Inparanoid	1	1.050	532	1.000	Inparanoid score	I1177
OMA	1	1.010	-	-		QHG63024
OrthoDB	1	1.010	-	-		D293770at33208
OrthoFinder	1	1.000	-	-		FOG0000848
OrthoInspector	1	1.000	-	-		otm26018
orthoMCL	1	0.900	-	-		OOG6_100668
Panther	1	1.100	-	-	O	PTHR20852
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R493
SonicParanoid	1	1.000	-	-		X534
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940