DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Or10a and GPROR56

DIOPT Version :9

Sequence 1:	NP_511122.1	Gene:	Or10a / 32086	FlyBaseID:	FBgn0030298	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_313638.1	Gene:	GPROR56 / 1274503	VectorBaseID:	AGAP004356	Length:	400	Species:	Anopheles gambiae

Alignment Length:	430	Identity:	85/430 - (19%)
Similarity:	169/430 - (39%)	Gaps:	88/430 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FAVPRLS---LDIMGYWPGKTGDTWPWRSLIHFAILAIGVATELHAGMCFL--DRQQITLALETL 78
            |.:.:||   |.|:.:|....|...|...|:   :.||.....|.....||  .:..||..::..
Mosquito    10 FPLVKLSTKLLRIIRFWNDSPGQRIPSLGLL---VTAIYPLIWLIPSWLFLVSSQDNITRFMKAA 71

  Fly    79 CPAGTSAVTLLKM-FLMLRFRQDLSIMWNRL--------RGLLFDPNWERPEQRDIR--LKHSAM 132
            ......::...|: |..:.||:     |.:|        ..:|.:||.|      |:  |.|...
Mosquito    72 NEQIVFSLICCKLCFYAIHFRR-----WEKLYYDLQRSFSTVLNNPNLE------IQTILGHVTK 125

  Fly   133 AA-RINFWPLSAGFFTCTTYNLKPILIAMILY-------------LQNRY-------EDFVWFTP 176
            :. ::..:..|...|.|..|.|.|:|..::.|             ::.:|       ..:||. |
Mosquito   126 STHKLTKYYCSTVSFNCAAYGLFPMLFIVVKYAVTGSYDVPLSTPIEAKYFIPGLRTNFWVWL-P 189

  Fly   177 FNMTMPKVLLNYPFFPLTYIFIAYTGYVTIFMFGGCDGFYFEFCAHLSALFEVLQAEIESMFRPY 241
            .::|:..:|             ...|:..:|:    :.|.:......|.:|.:||.::..:....
Mosquito   190 VDLTLNAIL-------------ELHGFALVFV----ETFTWNLVYATSCMFRILQIQVNELSHQS 237

  Fly   242 TDHLELSPVQLYILEQKMRSVIIRHNAIIDLTRFFRDRYTIITLAHFVSAAMVIGFSMVNLLTLG 306
            .:..|.:        .|:::.|..|::::.......:..::..|..::|..:.:...|| :|:|.
Mosquito   238 RNEKEWN--------GKLKTFIALHDSVLRSAETLEEILSLQMLLLYISTILALCLGMV-VLSLA 293

  Fly   307 NNGLGAMLYVAYTVAA-----LSQLLVYCYGGTLVAESSTGLCRAMFSCPWQLFKPKQRRLVQLL 366
            .|    .:||..|..|     :.|...:.|.||.:.|.|..:..|:|...|...|..:::.:..|
Mosquito   294 VN----EVYVLLTTMAVFGYCIFQTFSFSYLGTELIEQSEAVADAIFHSKWYTQKLNRQKDMCFL 354

  Fly   367 ILRSQRPVSM-AVPFFSPSLATFAAILQTSGSIIALVKSF 405
            ::|:.:||.: |...|..:..:|..:::.:.:|..|:..|
Mosquito   355 MMRANKPVKLTAAKLFVVTRDSFTQVIKQAYTIFTLMSQF 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or10a	NP_511122.1	7tm_6	70..396	CDD:251636	68/363 (19%)
GPROR56	XP_313638.1	7tm_6	<220..385	CDD:251636	36/177 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910