| Sequence 1: | NP_001162718.1 | Gene: | dlg1 / 32083 | FlyBaseID: | FBgn0001624 | Length: | 1030 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001354650.1 | Gene: | CASK / 8573 | HGNCID: | 1497 | Length: | 926 | Species: | Homo sapiens |
| Alignment Length: | 395 | Identity: | 85/395 - (21%) |
|---|---|---|---|
| Similarity: | 163/395 - (41%) | Gaps: | 62/395 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 625 TNGSEKNLE---NVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQSQSQL 686
Fly 687 A------TSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRA-----------VS 734
Fly 735 TEDITREPRTITIQKG---PQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNV 796
Fly 797 NLTHATHEEAAQALKTSGGVVT--LLAQYRPEEYNRFEARIQELKQQAALGAGGSGT----LLRT 855
Fly 856 TQK--RSLYVRALFDYDPNRDDGLPSR--GLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIG 916
Fly 917 IVPSK--RRWERKMRARDRSVKFQGHAAANNNLDKQSTLDR--KKKNFTFSR----------KFP 967
Fly 968 FMKSR 972 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dlg1 | NP_001162718.1 | L27_1 | 303..359 | CDD:286187 | |
| PDZ | 454..540 | CDD:214570 | |||
| PDZ_signaling | 566..655 | CDD:238492 | 10/32 (31%) | ||
| PDZ_signaling | 742..820 | CDD:238492 | 18/82 (22%) | ||
| SH3_DLG-like | 862..922 | CDD:212795 | 24/63 (38%) | ||
| CASK | NP_001354650.1 | STKc_CASK | 8..307 | CDD:270996 | |
| Calmodulin-binding | 305..315 | ||||
| L27 | 348..401 | CDD:197794 | 12/48 (25%) | ||
| L27 | 406..456 | CDD:397114 | 4/49 (8%) | ||
| Required for interaction with NRXN1 (via C-terminal tail). /evidence=ECO:0000250|UniProtKB:Q62915 | 482..909 | 66/265 (25%) | |||
| PDZ_signaling | 488..568 | CDD:238492 | 18/82 (22%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 574..610 | 6/35 (17%) | |||
| SH3_CASK | 616..677 | CDD:213014 | 24/62 (39%) | ||
| Guanylate_kin | 738..911 | CDD:395500 | 1/3 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||