DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dlg1 and SYNJ2BP

DIOPT Version :9

Sequence 1:	NP_001162718.1	Gene:	dlg1 / 32083	FlyBaseID:	FBgn0001624	Length:	1030	Species:	Drosophila melanogaster
Sequence 2:	NP_060843.2	Gene:	SYNJ2BP / 55333	HGNCID:	18955	Length:	145	Species:	Homo sapiens

Alignment Length:	131	Identity:	50/131 - (38%)
Similarity:	69/131 - (52%)	Gaps:	10/131 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 VNGDDSWLY--EDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDII 506
            :||...:|.  |:|.|.||.|||||:|.||||..::..|:.||::::...||||.||||...|.|
Human     1 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKI 65

  Fly   507 VSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDL 571
            :|||...:.::.|..|||..:.||..|.|.|:.:......|......||        |..|.|.:
Human    66 LSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGD--------PSGIPIFM 122

  Fly   572 V 572
            |
Human   123 V 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dlg1	NP_001162718.1	L27_1	303..359	CDD:286187
		PDZ	454..540	CDD:214570	39/85 (46%)
		PDZ_signaling	566..655	CDD:238492	3/7 (43%)
		PDZ_signaling	742..820	CDD:238492
		SH3_DLG-like	862..922	CDD:212795
SYNJ2BP	NP_060843.2	PDZ_signaling	13..97	CDD:238492	38/83 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910