Protein Alignment dlg1 and pals2b

DIOPT Version :9

• Sequence 1: NP_001162718.1
• Gene: dlg1 / 32083
• FlyBaseID: FBgn0001624
• Length: 1030
• Species: Drosophila melanogaster
• Sequence 2: XP_005170070.1
• Gene: pals2b / 394134
• ZFINID: ZDB-GENE-040426-775
• Length: 580
• Species: Danio rerio
• Alignment Length: 501
• Identity: 121/501 - (24%)
• Similarity: 186/501 - (37%)
• Gaps: 166/501 - (33%)

  Fly   566 VIEID-LVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDG----GAAQ--VD--GRL--SIGDK 619
            ::.:| ....|.||. |.|||.      |:.|..|::|.:|    ||.|  :|  |.|  :.|.|
Zfish     2 ILTVDETFSNGAGLN-SDAGGF------GETGEGVSELDEGADPSGAMQQVLDNLGELPSTTGAK 59

  Fly   620 LI------------AVRTNG-SEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGG 671
            .|            .||:.. :.:.||:|..|   |..::..:.||.|:|....|:..
Zfish    60 DIDLIFLKGIMESPIVRSLAKAHERLEDVKLE---AVQENNVELVTDILGDISGLSVR------- 114

  Fly   672 GLSSGQQLSQSQSQLATSQSQSQVHQQQH------ATPMVNSQSTEPGSRYASTNVLAAVPPGTP 730
                    ..|.::|      |::.|:.|      |..||.|:..|           |..||...
Zfish   115 --------DDSAAEL------SKILQEPHFQSLLEAHDMVASKCYE-----------APAPPELT 154

  Fly   731 RAVSTEDITREP---RTITIQK---GPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQ 789
            ...:..:...:.   |.|.|:|   .|.|:.|.:..|:    :.::.||.||..|....|..||.
Zfish   155 NDAAVNNALMQADAVRMIGIRKKAGEPLGVTFRMDKGD----LVIARILHGGLIDRQGLLHVGDI 215

  Fly   790 LLSVNNVNL-THATHEEAAQALKTSGGVVTL--LAQYR----PEEYNRFEARIQELKQQAALGAG 847
            :..||..:: |:.|  |..:.||...|.:||  |..||    |.:
Zfish   216 IKEVNGKDVGTNPT--ELQEMLKECSGGITLKILPSYRDAPAPPQ-------------------- 258

  Fly   848 GSGTLLRTTQKRSLYVRALFDYDPNRDDGLPSR--GLPFKHGDILHVTNASDDEWWQARRVLGDN 910
                         :||:..|||:|..|:.:|.|  ||.||.||||.:.|..|..||||..:
Zfish   259 -------------VYVKPHFDYNPASDNLIPCREAGLAFKRGDILQIVNREDPNWWQACHL---- 306

  Fly   911 EDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEK 975
            .:...|::||:...|::.....|.:...|...        .|:..|||     :|
Zfish   307 AEGGTGLIPSQFLEEKRKAFVPRDLDGAGILC--------GTMTGKKK-----KK---------- 348

  Fly   976 NEDGSDQEPFMLCYTQDDANAEGGEI-IYR--VELPDMEQITLIYL 1018
                      |:..|..:|..:..|: ||.  ..:|..::.|||.:
Zfish   349 ----------MMYLTAKNAEFDRHELQIYEEVARMPPFQRKTLILI 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlg1	NP_001162718.1	L27_1	303..359	CDD:286187
		PDZ	454..540	CDD:214570
		PDZ_signaling	566..655	CDD:238492	31/112 (28%)
		PDZ_signaling	742..820	CDD:238492	26/86 (30%)
		SH3_DLG-like	862..922	CDD:212795	26/61 (43%)
pals2b	XP_005170070.1	L27	43..96	CDD:197794	14/55 (25%)
		L27	98..149	CDD:280918	16/82 (20%)
		PDZ_signaling	169..247	CDD:238492	26/83 (31%)
		SH3_MPP	260..317	CDD:212796	25/60 (42%)
		Guanylate_kin	377..567	CDD:279019	3/8 (38%)
		GuKc	387..568	CDD:214504

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910