DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dlg1 and mpp7a

DIOPT Version :9

Sequence 1:	NP_001162718.1	Gene:	dlg1 / 32083	FlyBaseID:	FBgn0001624	Length:	1030	Species:	Drosophila melanogaster
Sequence 2:	XP_021335692.1	Gene:	mpp7a / 30166	ZFINID:	ZDB-GENE-991209-8	Length:	621	Species:	Danio rerio

Alignment Length:	263	Identity:	66/263 - (25%)
Similarity:	111/263 - (42%)	Gaps:	43/263 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   674 SSGQQLSQSQSQLATSQSQSQVHQ------QQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRA 732
            |:|...:....:|....:.:::.:      :.|...:::...|.....|.        |...|..
Zfish    71 SAGSLAADLTEELQARSASNEIRELVKLLSKPHVKSLLSVHDTVAKKSYD--------PELPPLP 127

  Fly   733 VSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVN 797
            ...:|.....:.|.:.|..:.||..|...|....|.|:.||.||.||....:..||:|..||.:.
Zfish   128 DDIDDEEDSVKIIRLVKNKEPLGATIKKDEHTGAILVARILRGGAADRSGLIHVGDELKEVNGIP 192

  Fly   798 LTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLRTTQKRSLY 862
            :.....||..:.|..|.|.:|...             :..:|.:|            .:::..::
Zfish   193 VDDKKPEEIIRILSQSQGAITFKV-------------VPGIKDEA------------QSKEPKMF 232

  Fly   863 VRALFDYDPNRDDGLPSR--GLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWE 925
            ::|||||:|..|..:|.:  ||.||.||||.|.:..|..|||| ::.||. :.:.|::|||...|
Zfish   233 IKALFDYNPAEDKAIPCKEAGLGFKKGDILQVMSQDDATWWQA-KLEGDG-NLRAGLIPSKHFQE 295

  Fly   926 RKM 928
            |::
Zfish   296 RRL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dlg1	NP_001162718.1	L27_1	303..359	CDD:286187
		PDZ	454..540	CDD:214570
		PDZ_signaling	566..655	CDD:238492
		PDZ_signaling	742..820	CDD:238492	25/77 (32%)
		SH3_DLG-like	862..922	CDD:212795	27/61 (44%)
mpp7a	XP_021335692.1	L27	12..68	CDD:197794
		L27	74..125	CDD:197794	5/58 (9%)
		PDZ_signaling	137..217	CDD:238492	25/92 (27%)
		SH3	232..292	CDD:327375	27/61 (44%)
		GuKc	403..608	CDD:214504
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910