Protein Alignment hop and Matk

DIOPT Version :10

• Sequence 1: NP_511119.2
• Gene: hop / 32080
• FlyBaseID: FBgn0004864
• Length: 1177
• Species: Drosophila melanogaster
• Sequence 2: XP_038935769.1
• Gene: Matk / 60450
• RGDID: 69058
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 106/317 - (33%)
• Similarity: 154/317 - (48%)
• Gaps: 59/317 - (18%)

  Fly   898 IGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTDFHREIGIMRTLSHPNIVKF------- 955
            ||.|.:|.|.:|       :...::||:|.:.....:..|..|..:|..|.|.|:|:.
  Rat   200 IGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHH 257

  Fly   956 -KYWAEKSHCIIMEYLQSGSFDIYLRFTAPNL-NNPRLVSFALDIANGMKYLSDMGLIHRDLAAR 1018
             .|       |:||::..|:...:||.....| :..:|:.|||.:|.||:||....|:|||||||
  Rat   258 GLY-------IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAAR 315

  Fly  1019 NILVDHNGDGDCV-KISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGV 1082
            ||||..    |.| |:||||||:.....|   ..|.| :|::|.:|||:...||||.|||||:||
  Rat   316 NILVSE----DLVAKVSDFGLAKAELRKG---LDSSR-LPVKWTAPEALKNGRFSSKSDVWSFGV 372

  Fly  1083 TLFEMFSRGEEP--------------------------NLVPIQTSQEDFLNRLQSGERLNRPAS 1121
            .|:|:||.|..|                          .|.|...|.::....::.|.|:..|.|
  Rat   373 LLWEVFSYGRAPYPKMVSSTPGRAACASRVTDCPHPCYPLPPYLQSLKEVSEAVEKGYRMEPPDS 437

  Fly  1122 CPDFIYDLMQLCWHATPRSRPSFATIVDIITREV-ATKVTHPTDGHQSPPNQPTDAE 1177
            ||..::.||..||.|.|..||.|..||:.:.||: :..|..|..|.::..:.||.::
  Rat   438 CPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGRELRSVGVAAPAGGQEAEGSAPTRSQ 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633
		PTKc_Jak_rpt2	886..1155	CDD:270634	100/292 (34%)
Matk	XP_038935769.1	SH3	9..67	CDD:473055
		SH2_csk_like	77..174	CDD:198190
		Protein Kinases, catalytic domain	187..470	CDD:473864	99/291 (34%)