DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hop and Ptk6

DIOPT Version :9

Sequence 1:	NP_511119.2	Gene:	hop / 32080	FlyBaseID:	FBgn0004864	Length:	1177	Species:	Drosophila melanogaster
Sequence 2:	NP_001102438.1	Gene:	Ptk6 / 366275	RGDID:	1309098	Length:	451	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	95/258 - (36%)
Similarity:	135/258 - (52%)	Gaps:	21/258 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   898 IGRGHYGTVYKGHLEFNDKDQPREQVAIKML---NTMQVSTDFHREIGIMRTLSHPNIVKFKYWA 959
            :|.|::|.|::|..      :...:||:|::   |.:...| |..||..|:.|.|.:|:.....|
  Rat   197 LGSGYFGEVFEGLW------KGLVRVAVKVISRDNLLHQHT-FQAEIQAMKKLRHKHILSLYAVA 254

  Fly   960 EKSH--CIIMEYLQSGSFDIYLRFT-APNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNIL 1021
            ....  .||.|.:..||....||.: ..:|....||.||..:|.||.||.....|||||||||:|
  Rat   255 TAGDPVYIITELMPKGSLLQLLRDSDEKDLPILELVDFASQVAEGMCYLESQNYIHRDLAARNVL 319

  Fly  1022 VDHNGDGDCVKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFE 1086
            |..|   :..|:.|||||:....|  .|.....::|.:|.:|||:|...:|..|||||:||.|.|
  Rat   320 VTEN---NLCKVGDFGLARLVKED--IYLSRDHNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHE 379

  Fly  1087 MFSRGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVD 1149
            :||||:.|  .|..::.|.|| |:.:|.|:..|..||..|:.||..||...|:.||.|..:.:
  Rat   380 IFSRGQMP--YPGMSNHETFL-RVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCE 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633
		PTKc_Jak_rpt2	886..1155	CDD:270634	95/258 (37%)
		TyrKc	894..1151	CDD:197581	95/258 (37%)
Ptk6	NP_001102438.1	SH3_Brk	12..69	CDD:212781
		SH2_PTK6_Brk	75..174	CDD:198221
		PKc_like	184..444	CDD:304357	95/258 (37%)
		STYKc	192..441	CDD:214568	95/258 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810