Protein Alignment hop and Txk

DIOPT Version :9

• Sequence 1: NP_511119.2
• Gene: hop / 32080
• FlyBaseID: FBgn0004864
• Length: 1177
• Species: Drosophila melanogaster
• Sequence 2: XP_036020891.1
• Gene: Txk / 22165
• MGIID: 102960
• Length: 543
• Species: Mus musculus
• Alignment Length: 592
• Identity: 152/592 - (25%)
• Similarity: 233/592 - (39%)
• Gaps: 158/592 - (26%)

  Fly   611 SVTMKMLKSDGNFMEFFRLAQTWSLIQSPQFLKLYGLTLADPYTMVMEYSRYGPLNKFLHSMPN- 674
            ||..:.:::..:......|::..|..|.|.|.||.|.|.::  ...::.|:..||.......|:
Mouse    50 SVQKRQVRTQISLSREEELSEKHSQRQRPWFAKLMGKTQSN--RGGVQPSKRKPLPPLPQEPPDE 112

  Fly   675 -VTLHCLLDLMH------GLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKISDPGYPR 732
             :.:..|.|.:.      .|.|...||    |:.   ||        ||:.:....:..:.|.
Mouse   113 RIQVKALYDFLPREPGNLALKRAEEYL----ILE---RC--------DPHWWKARDRFGNEGL-- 160

  Fly   733 PYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQKNLDGNI 797
                     ||..|....:.|..:           |||.:.:   :::..:.|:||||:..:|..
Mouse   161 ---------IPSNYVTENRLANLE-----------IYEWYHK---NITRNQTERLLRQEAKEGAF 202

  Fly   798 LKMLDQDICPAPIFETIMDGWSDDETKRFSHH------DIFSRLNTIKAEILPNYMPPPEIATNG 856
            :                         .|.|.|      .:|:|........:.:|    :|..|.
Mouse   203 I-------------------------VRDSRHLGSYTISVFTRARRHTQSSIKHY----QIKKND 238

  Fly   857 TGDETVIDRSDIPFLP------------------FPRSNMLMVIPLTSECRVIYNMENM------ 897
            :|...:.:|...|.:|                  :|...:...:|.||.    ::.|..
Mouse   239 SGQWYITERHLFPSVPELIQYHQYNAAGLISRLRYPIGLLGSCLPATSG----FSYEKWEIDPSE 299

  Fly   898 ------IGRGHYGTVYKG----HLEFNDKDQPREQVAIKMLNTMQVS-TDFHREIGIMRTLSHPN 951
                  ||.|.:|.|:.|    |:          .||||.:|...:| .||..|..:|..|||..
Mouse   300 LAFVKEIGSGQFGVVHLGEWRAHI----------PVAIKAINEGSMSEEDFIEEAKVMMKLSHSR 354

  Fly   952 IVKFKYWA---EKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHR 1013
            :|:. |..   :|...|:.|::::|....|||.....|....|:|...||..||.||.....|||
Mouse   355 LVQL-YGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYLERSCYIHR 418

  Fly  1014 DLAARNILVDHNGDGDC-VKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDV 1077
            ||||||.||    ...| |||||||:|::. .|..|.:.|....|::|..||.....::||.|||
Mouse   419 DLAARNCLV----SSACVVKISDFGMARYV-LDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDV 478

  Fly  1078 WSYGVTLFEMFSRGEEP-----NLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHAT 1137
            ||:||.::|:|:.|:.|     ||..::.        :..|.||.||...|..||.:|..|||.|
Mouse   479 WSFGVLMWEVFTEGKMPFENKSNLQVVEA--------ISQGFRLYRPHLAPMTIYRVMYSCWHET 535

  Fly  1138 PRSRPSF 1144
             ..:|.|
Mouse   536 -LQKPVF 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633	45/238 (19%)
		PTKc_Jak_rpt2	886..1155	CDD:270634	97/285 (34%)
		TyrKc	894..1151	CDD:197581	96/277 (35%)
Txk	XP_036020891.1	SH3_TXK	114..168	CDD:212840	15/79 (19%)
		SH2_Tec_Txk	172..277	CDD:198261	23/147 (16%)
		PKc_like	295..543	CDD:419665	95/272 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900