DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hop and Ptk6

DIOPT Version :9

Sequence 1:	NP_511119.2	Gene:	hop / 32080	FlyBaseID:	FBgn0004864	Length:	1177	Species:	Drosophila melanogaster
Sequence 2:	NP_033210.1	Gene:	Ptk6 / 20459	MGIID:	99683	Length:	451	Species:	Mus musculus

Alignment Length:	268	Identity:	97/268 - (36%)
Similarity:	137/268 - (51%)	Gaps:	35/268 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   898 IGRGHYGTVY----KGHLEFNDKDQPREQVAIKML---NTMQVSTDFHREIGIMRTLSHPNIVKF 955
            :|.|::|.|:    ||.:          .||:|::   |.:...| |..||..|:.|.|.:|:..
Mouse   197 LGAGYFGEVFEALWKGQV----------HVAVKVISRDNLLHQHT-FQAEIQAMKKLRHKHILSL 250

  Fly   956 KYWAEKSH--CIIMEYLQSGSFDIYLRFT----APNLNNPRLVSFALDIANGMKYLSDMGLIHRD 1014
            ...|....  .||.|.:..|:....||.:    .|.|   .||.||..:|.||.||.....||||
Mouse   251 YAVATAGDPVYIITELMPKGNLLQLLRDSDEKALPIL---ELVDFASQVAEGMCYLESQNYIHRD 312

  Fly  1015 LAARNILVDHNGDGDCVKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWS 1079
            |||||:||..|   :..|:.|||||:....|  .|...:.::|.:|.:|||:|...:|..|||||
Mouse   313 LAARNVLVTEN---NLCKVGDFGLARLVKED--IYLSHEHNVPYKWTAPEALSRGHYSIKSDVWS 372

  Fly  1080 YGVTLFEMFSRGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSF 1144
            :||.|.|:||||:.|  .|..::.|.|| |:.:|.|:..|..||..|:.||..||...|:.||.|
Mouse   373 FGVLLHEIFSRGQMP--YPGMSNHETFL-RVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCF 434

  Fly  1145 ATIVDIIT 1152
            ..:.:.:|
Mouse   435 KDLCEKLT 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633
		PTKc_Jak_rpt2	886..1155	CDD:270634	97/268 (36%)
		TyrKc	894..1151	CDD:197581	96/265 (36%)
Ptk6	NP_033210.1	SH3	12..69	CDD:302595
		SH2_PTK6_Brk	75..174	CDD:198221
		Linker	171..190
		PKc_like	184..444	CDD:304357	97/268 (36%)
		STYKc	192..441	CDD:214568	96/265 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810