DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hop and Matk

DIOPT Version :9

Sequence 1:	NP_511119.2	Gene:	hop / 32080	FlyBaseID:	FBgn0004864	Length:	1177	Species:	Drosophila melanogaster
Sequence 2:	XP_006513357.1	Gene:	Matk / 17179	MGIID:	99259	Length:	506	Species:	Mus musculus

Alignment Length:	291	Identity:	105/291 - (36%)
Similarity:	155/291 - (53%)	Gaps:	37/291 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   898 IGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTDFHREIGIMRTLSHPNIVKF------- 955
            ||.|.:|.|.:|       :...::||:|.:.....:..|..|..:|..|.|.|:|:.
Mouse   240 IGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHH 297

  Fly   956 -KYWAEKSHCIIMEYLQSGSFDIYLRFTAPNL-NNPRLVSFALDIANGMKYLSDMGLIHRDLAAR 1018
             .|       |:||::..|:...:||.....| :..:|:.|||.:|.||:||....|:|||||||
Mouse   298 GLY-------IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAAR 355

  Fly  1019 NILVDHNGDGDCV-KISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGV 1082
            ||||..    |.| |:||||||: |...|   ..|.| :|::|.:|||:...||||.|||||:||
Mouse   356 NILVSE----DLVAKVSDFGLAK-AERKG---LDSSR-LPVKWTAPEALKNGRFSSKSDVWSFGV 411

  Fly  1083 TLFEMFSRGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATI 1147
            .|:|:||.|..|  .| :.|.::....::.|.|:..|..||..::.||..||.|.|..||.|..|
Mouse   412 LLWEVFSYGRAP--YP-KMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKI 473

  Fly  1148 VDIITREV-ATKVTHPTDGHQSPPNQPTDAE 1177
            |:.:.||: :..|:.|..|.::..:.||.::
Mouse   474 VEKLGRELRSVGVSAPAGGQEAEGSAPTRSQ 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633
		PTKc_Jak_rpt2	886..1155	CDD:270634	99/266 (37%)
		TyrKc	894..1151	CDD:197581	98/262 (37%)
Matk	XP_006513357.1	SH3	49..107	CDD:388381
		SH2_csk_like	117..214	CDD:198190
		PKc_like	227..480	CDD:389743	98/265 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810