| Sequence 1: | NP_511119.2 | Gene: | hop / 32080 | FlyBaseID: | FBgn0004864 | Length: | 1177 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001177759.1 | Gene: | Jak3 / 16453 | MGIID: | 99928 | Length: | 1100 | Species: | Mus musculus |
| Alignment Length: | 1242 | Identity: | 300/1242 - (24%) |
|---|---|---|---|
| Similarity: | 479/1242 - (38%) | Gaps: | 269/1242 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 16 SGRTSLADSASLTNSSLRSGTSSQSIHT-----NDGTIRVFNFTTGEFERFHPNMLCEEICNTMC 75
Fly 76 RQLGIAPIAQLLYGI--REHSTSRRPSPLVRLDLTWCLPGERLNCQLVYCFRMRFRVPE------ 132
Fly 133 -------LDSQLELIDGRSHKFLYRQMRYDMRTEQIPEIRYPEHKDKSTGLAVMDMLIDDQEQSE 190
Fly 191 DQQAMRSIEKL----YKLYLPPSL---WRAHSFFVGSKIRE----VFRSLKANSLSVERLKWHYV 244
Fly 245 HQVSHLAPTYMTEQFTCTVQYLPNEE----VARGSGPIGTSLAHSTSTLASSGSTNTLSTLTTNT 305
Fly 306 NSVALGGSGKKAKRRSTSGGIDVYVRVFPHDSLEPGLKVARVTSEATLKWILVGAVEGIFMISKI 370
Fly 371 NDTSVRLEIVGLPKGYEMQFQTEKEMKSFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCH 435
Fly 436 GPIGGAYSLMKLHENGDKCGSYIVRECDREYNIYYID--INTKIMAKKTDQERCKTETFRIVRKD 498
Fly 499 SQWKLSYNNGEHVLNSLHEVAHIIQADSPDRYRIPASKYDKPPLLLLLLPKNLKAKKTDL----- 558
Fly 559 ------------------QLSEAELQRRNPQIFNPRTDLQWYPDSISLSDDGMMFTMRGDWIQQS 605
Fly 606 PVKDVSVTMKMLKS-DGNFME-FFRLAQTWSLIQSPQFLKLYGLTLADPYTMVMEYSRYGPLNKF 668
Fly 669 LHSMPN-VTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKISDPGYPR 732
Fly 733 PYRESDS-----PWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLR--------- 783
Fly 784 -QEQL--LRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPN 845
Fly 846 YMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECR--VIYNME-----NMIGRGHY 903
Fly 904 GTVYKGHLE-FNDKDQPREQVAIKML--NTMQVSTDFHREIGIMRTLSHPNIVKFK---YW-AEK 961
Fly 962 SHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNG 1026
Fly 1027 DGDCVKISDFGLAQFAN-SDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFS- 1089
Fly 1090 --------------RGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRS 1140
Fly 1141 RPSFATI 1147 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| hop | NP_511119.2 | B41 | 39..259 | CDD:214604 | 57/250 (23%) |
| SH2_Jak_family | 420..516 | CDD:198177 | 23/97 (24%) | ||
| PTK_Jak_rpt1 | 584..836 | CDD:270633 | 56/271 (21%) | ||
| PTKc_Jak_rpt2 | 886..1155 | CDD:270634 | 103/292 (35%) | ||
| TyrKc | 894..1151 | CDD:197581 | 101/282 (36%) | ||
| Jak3 | NP_001177759.1 | Interaction with cytokine/interferon/growth hormone receptors. /evidence=ECO:0000250 | 1..223 | 56/242 (23%) | |
| B41 | 41..246 | CDD:214604 | 51/225 (23%) | ||
| FERM_C_JAK3 | 250..359 | CDD:275413 | 32/168 (19%) | ||
| SH2 | 359..455 | CDD:301589 | 26/107 (24%) | ||
| PKc_like | 517..774 | CDD:304357 | 59/279 (21%) | ||
| Pkinase_Tyr | 517..773 | CDD:285015 | 59/278 (21%) | ||
| PKc_like | 813..1095 | CDD:304357 | 101/284 (36%) | ||
| Pkinase_Tyr | 818..1091 | CDD:285015 | 101/279 (36%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 247 | 1.000 | Inparanoid score | I3247 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG47769 | |
| OrthoDB | 1 | 1.010 | - | - | D38412at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001105 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42587 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | LDO | PTHR45807 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X669 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 11 | 10.940 | |||||