| Sequence 1: | NP_511119.2 | Gene: | hop / 32080 | FlyBaseID: | FBgn0004864 | Length: | 1177 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_038510.2 | Gene: | Btk / 12229 | MGIID: | 88216 | Length: | 659 | Species: | Mus musculus |
| Alignment Length: | 478 | Identity: | 125/478 - (26%) |
|---|---|---|---|
| Similarity: | 190/478 - (39%) | Gaps: | 124/478 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 736 ESDSPW------------IPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLL 788
Fly 789 RQKNLDGNILKMLDQD-------------------------ICPAP----------IFETIMDGW 818
Fly 819 SDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIP 883
Fly 884 LTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTD-FHREIGIMRTL 947
Fly 948 SHPNIVKFKYWAEKSH--CIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGL 1010
Fly 1011 IHRDLAARNILVDHNGDGDCVKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYS 1075
Fly 1076 DVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLN-----RLQSGERLNRPASCPDFIYDLMQLCWH 1135
Fly 1136 ATPRSRPSF----ATIVDIITRE 1154 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| hop | NP_511119.2 | B41 | 39..259 | CDD:214604 | |
| SH2_Jak_family | 420..516 | CDD:198177 | |||
| PTK_Jak_rpt1 | 584..836 | CDD:270633 | 24/146 (16%) | ||
| PTKc_Jak_rpt2 | 886..1155 | CDD:270634 | 91/281 (32%) | ||
| TyrKc | 894..1151 | CDD:197581 | 90/268 (34%) | ||
| Btk | NP_038510.2 | PH_Btk | 6..166 | CDD:269944 | |
| Inositol-(1,3,4,5)-tetrakisphosphate 1-binding. /evidence=ECO:0000250 | 12..24 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 171..210 | ||||
| SH3_BTK | 217..271 | CDD:212839 | 7/24 (29%) | ||
| SH2_Tec_Btk | 274..378 | CDD:198260 | 18/125 (14%) | ||
| PTKc_Btk_Bmx | 397..652 | CDD:173657 | 93/296 (31%) | ||
| Inhibitor-binding. /evidence=ECO:0000250 | 474..479 | 2/4 (50%) | |||
| CAV1-binding. /evidence=ECO:0000250 | 581..588 | 3/6 (50%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||