Protein Alignment hop and lck

DIOPT Version :9

• Sequence 1: NP_511119.2
• Gene: hop / 32080
• FlyBaseID: FBgn0004864
• Length: 1177
• Species: Drosophila melanogaster
• Sequence 2: XP_012812855.2
• Gene: lck / 100497656
• XenbaseID: XB-GENE-6054021
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 137/522 - (26%)
• Similarity: 213/522 - (40%)
• Gaps: 118/522 - (22%)

  Fly   694 LEDNKIIHNYIRCSNLYVTKYDP------------NSYVLDAKISDPGY-PRPYRESDSPWIPVK 745
            |.||.::..|         .|:|            ..:||:.|  |..: .:..|.....:||..
 Frog    55 LHDNLVVALY---------NYEPMHDEDLGFEAGEKLHVLEQK--DEWWKAKSLRTGQVGYIPYN 108

  Fly   746 YYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQE-QLLRQKNLDGNILKMLDQDICPAP 809
            :..::...:    :::|.|            .||.....| |||...|..|:.|.
 Frog   109 FVASVNGIE----SEMWFF------------RDLGRKDAERQLLAPGNQQGSFLV---------- 147

  Fly   810 IFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLP-- 872
                     .:.||.:.|:......|:..:.|::.:|    :|.....|...:..|.....|.
 Frog   148 ---------RESETTKGSYSLSVRDLDQNQGEVVKHY----KIRNLDNGGFYISPRKTFQTLQEL 199

  Fly   873 ---FPRSNMLMVIPLTSEC-----------------RVIYNMENMIGRGHYGTVYKGHLEFNDKD 917
               :.||:..:...|...|                 |....:...:|.|.:|.|:.|:...:.|
 Frog   200 VQHYRRSSDGLCTLLKEPCQTQRPQKPWWADEWEIPRNKLQLVKKLGAGQFGEVWMGYYNGHTK- 263

  Fly   918 QPREQVAIKMLNTMQVSTD-FHREIGIMRTLSHPNIVKFK-YWAEKSHCIIMEYLQSGSFDIYLR 980
                 ||||.|....:|.: |..|..:|:.|.||.:|:.. ...::...|:.||::.|....||:
 Frog   264 -----VAIKSLKPGTMSPEAFLAEANLMKQLQHPRLVRLNAVVTQEPIYIVTEYMEKGCLVDYLK 323

  Fly   981 FTAPNLNNP--RLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGDCVKISDFGLAQFAN 1043
             |:..|...  :|:..:..:|.||.:|.....|||||.|.||||   .:..|.||:|||||:..
 Frog   324 -TSEGLKLTIYKLIDMSAQVAEGMAFLEHKNYIHRDLRAANILV---SESLCCKIADFGLARVI- 383

  Fly  1044 SDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLN 1108
            .|..|.||.....||:|.:||||:...|:..|||||:||.|.|:.:.|..|  .|..|:.| .:.
 Frog   384 VDNEYTAKEGAKFPIKWTAPEAINYGTFTIKSDVWSFGVLLTEIVTYGRIP--YPGMTNPE-VIE 445

  Fly  1109 RLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSF----ATIVDIITREVATKVTHPTDG-HQS 1168
            .|:.|.|:.:|.:||..:|:||..||...|..||:|    :.:.|..|         .|:| :||
 Frog   446 NLERGYRMPQPDNCPMELYELMLRCWKEEPEERPTFEFLRSLLEDFFT---------ATEGPYQS 501

  Fly  1169 PP 1170
            .|
 Frog   502 QP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hop	NP_511119.2	B41	39..259	CDD:214604
		SH2_Jak_family	420..516	CDD:198177
		PTK_Jak_rpt1	584..836	CDD:270633	27/155 (17%)
		PTKc_Jak_rpt2	886..1155	CDD:270634	95/293 (32%)
		TyrKc	894..1151	CDD:197581	92/264 (35%)
lck	XP_012812855.2	SH3_Lck	59..112	CDD:212938	10/63 (16%)
		SH2_Src_family	117..217	CDD:199827	24/138 (17%)
		PTKc_Lck_Blk	231..494	CDD:270652	94/285 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910