Protein Alignment dsh and dsh

DIOPT Version :10

• Sequence 1: NP_511118.2
• Gene: dsh / 32078
• FlyBaseID: FBgn0000499
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_061499640.1
• Gene: dsh / 1274593
• VectorBaseID: AGAMI1_014295
• Length: 651
• Species: Anopheles gambiae
• Alignment Length: 614
• Identity: 434/614 - (70%)
• Similarity: 474/614 - (77%)
• Gaps: 74/614 - (12%)

  Fly     6 GGGQETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLNKQNNNYKYFFKSMDADFGVVKEEIA 70
            |||.||||||||||||||||||||:|:.||||:||||||||||.|||||||||||||||||||||
Mosquito    28 GGGGETKVIYHIDDETTPYLVKIPLPAPQVTLKDFKLVLNKQNINYKYFFKSMDADFGVVKEEIA 92

  Fly    71 DDSTILPCFNGRVVSWLVSADGTNQSDNCSELPTSECELGMGLTNRKLQQQQQQHQQQQQQQQQQ 135
            ||:||||||||:||||||:|||:|||| ||||..:|...|
Mosquito    93 DDATILPCFNGKVVSWLVTADGSNQSD-CSELQPTEMIDG------------------------- 131

  Fly   136 HQQQQQQQQQQVQPVQLAQQQQQQVLHHQKMMGNPLLQPPPLTYQSASVLSSDLDSTSLFGTESE 200
                        :|. |||.:.........||..|:   .|||||||||:||||||||||.||||
Mosquito   132 ------------RPT-LAQLRSMNKPTMNNMMNMPM---NPLTYQSASVVSSDLDSTSLFETESE 180

  Fly   201 LTLDRDMTDYSSVQRLQVRKKPQRRKKRAPSMSRTSSYSSITDSTMSLNIITVSINMEAVNFLGI 265
            :|||||||:.|||||||||||||||||||||||||||||||||||||||||||.|||:.||||||
Mosquito   181 ITLDRDMTECSSVQRLQVRKKPQRRKKRAPSMSRTSSYSSITDSTMSLNIITVQINMDTVNFLGI 245

  Fly   266 SIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPG 330
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   246 SIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPG 310

  Fly   331 PIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALTSHDSIIADIAEPIKERLDQN-NL 394
            ||||||||||||||||||||||||||||||||||||||.||.|.|:|..|:.|.:.|||..: ::
Mosquito   311 PIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTAALRSQDTINTDLPESVLERLHADMDM 375

  Fly   395 EEIVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYI 459
            ::||:|||||||||||||||||||||||||||||.|||:||:|:.:.||||||:.||.|||..||
Mosquito   376 KDIVRAMTKPDSGLEIRDRMWLKITIPNAFIGADVVNWILEHVDGIGDRREARKYVSLMLRRGYI 440

  Fly   460 KHTVNKLTFSEQCYYVVNEERNPNLLGRGHLHPHQLPHGHGGHALSHADTESITSDIGPLPNPPI 524
            |||||||||||||||||......::..                 :|..||||:.|||.|||||||
Mosquito   441 KHTVNKLTFSEQCYYVVGNGIRQDISN-----------------MSLEDTESMLSDIAPLPNPPI 488

  Fly   525 YMPYSATYNPSHGYQPIQYG-IAERHISSGSSSSDVLTSKDISASQSDITSVIHQANQLTIAAHG 588
            ||.||..||||||||||||| ..|||.||||||||:|||||.||||||:.:||.|.||:|| |:.
Mosquito   489 YMTYSGNYNPSHGYQPIQYGCTGERHPSSGSSSSDILTSKDTSASQSDLAAVIQQTNQMTI-ANA 552

  Fly   589 SNKSSGSSNRGGGGGGGGGGNNTNDQDVS 617
            |||||||||||            |:||:|
Mosquito   553 SNKSSGSSNRG------------NEQDIS 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsh	NP_511118.2	DAX	8..91	CDD:197474	73/82 (89%)
		Dishevelled	<174..248	CDD:460544	66/73 (90%)
		PDZ_Dishevelled-like	252..338	CDD:467201	82/85 (96%)
		DEP_dishevelled	395..478	CDD:239885	67/82 (82%)
dsh	XP_061499640.1	None