DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GCS1 and AT1G24320

DIOPT Version :9

Sequence 1:	NP_001245621.1	Gene:	GCS1 / 32073	FlyBaseID:	FBgn0030289	Length:	849	Species:	Drosophila melanogaster
Sequence 2:	NP_173842.2	Gene:	AT1G24320 / 839048	AraportID:	AT1G24320	Length:	789	Species:	Arabidopsis thaliana

Alignment Length:	797	Identity:	323/797 - (40%)
Similarity:	446/797 - (55%)	Gaps:	61/797 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RVNTPFDHQKMV---VHAGLEQPDRYWGSYRPLTYFGMKTRDPHSLVMGLMWYTPSNLGPGGQGI 143
            ||.|||...|:.   :..|..:...|||:|||..|||::.|.|.|||.||||..   :..|...:
plant    22 RVITPFPSPKLTDLSMFQGEHKESLYWGTYRPQMYFGVRARTPKSLVAGLMWLV---MKDGKPVM 83

  Fly   144 RHWCEQGDKLDSYGWTHHDGRSFGVQEIQDLPFELKTSFVKYPEGK-QYGGDWTARISVRNTTRA 207
            ||:||..:.|.|:||..|:||.||.||:.:....|:|||||..||. .|||||:.||:|:|....
plant    84 RHFCENSNDLKSFGWKEHNGRDFGRQELFEQNMVLETSFVKSEEGSLGYGGDWSIRINVQNMLND 148

  Fly   208 WD--KSISLIWYVALDERTNGHI--KYVSDDKSPEPGVYGEAQGLGEFQVRFHAVKGKILHKSYL 268
            .:  :|..|.:|:| ||..||..  |.|...|.......|..|.:|.:|:  |......|...|.
plant   149 DEVKRSTHLFFYLA-DEGCNGVNLGKDVLRLKESSVLASGSRQDVGNWQM--HLKSQNHLETHYC 210

  Fly   269 STVAPSLAKLKDTLFSHFRAFADKRGNRFIGLPGEIVSQNGLPSSNPEPNFIAIQITAEVDFTLD 333
            ....|.:..|...:..:..|..:|.|...:.           .||....|....||:.....|:|
plant   211 GFKTPDIVNLSGLVQQNLTAQEEKSGLLQLS-----------DSSEDSSNIYVFQISTTNQSTID 264

  Fly   334 ITY-----QSTSGFSLGESIPKPPTGRAYQDSLQAKIAQFEQRFEDRFQLKQKGHSPEEVRFARN 393
            |.:     :.||..   |:.....||......|:.|...|..:|.:.|.|..| ..||.:...:.
plant   265 IAFVSGIKEETSNM---ENRIMSLTGLPLSSLLEEKHIAFNAKFNECFNLSDK-LDPETLVVGKA 325

  Fly   394 ALSNLLGGIGYFYGSSRVQSVYTKNPVP--------YWKAPLYTAVPSRSFFPRGFLWDEGFHGL 450
            |:.|:|||||||||.|::.  :.|:|:.        ||.|.||||||||..||||||||||||.|
plant   326 AIGNMLGGIGYFYGQSKIH--FPKSPLAKSEDDFLLYWPAELYTAVPSRPRFPRGFLWDEGFHQL 388

  Fly   451 LISAWDIDIELDIICHWFDLLNVEGWIPREQILGVEALAKVPEEFVTQRNSNANPPTFFLTLKKL 515
            ||..||:.|.|:|:.:|.||:|::|||||||:||.|||:|:|:::|.|..||.||||..|.::.|
plant   389 LIWRWDVHITLEIVGNWLDLMNIDGWIPREQVLGAEALSKIPKQYVVQFPSNGNPPTLLLVIRDL 453

  Fly   516 LTSHRA----ELSQNGRLATLERLYPRVQAWFNWFNTTQRGEVLGTYLWRGRNATTTRELNPKSL 576
            :...|.    |..::..|:.|:|.:.|:.|||.||||:|.|:..|:|.|.||:..|.|||||:||
plant   454 INGIRTEKFNEADRDKILSFLDRAFVRLDAWFKWFNTSQIGKEKGSYYWHGRDNITNRELNPQSL 518

  Fly   577 SSGLDDYPRASHPTDKERHLDLRCWIALAAGVMAELSTLLGKDD----AKYYETASYLTDNVRLN 637
            |||||||||||||.:.|||:|||||:.|||..|..:...:||:|    ..|...|..|:|...||
plant   519 SSGLDDYPRASHPNEDERHVDLRCWMYLAADSMNSIQEFMGKNDILVTEDYSSIAKLLSDFTLLN 583

  Fly   638 RLHLAPYSEQYADWGLHTDQVKLKRPPSMAPQQQQRHHHQHYQLPEMQRVTGELPTYQFVDSAFG 702
            ::|.......|.|:|.||::|:|        ..::..|...:...|:.|.|...|..:.|.. .|
plant   584 QMHYDKDHGAYLDFGNHTEEVRL--------VWKEVIHEDGHLSRELVRETYGKPELRLVPH-IG 639

  Fly   703 YVSLFPLLLEQLDHDSPYLTKLLNDLRDPEQLWTNYGLRSLSKRSPLYMQRNTEHDPPYWRGPIW 767
            |||.||.:...:..||..|.|.|:.:.:...:|::|||.||:|.|.|||:.|:||..|||||.||
plant   640 YVSFFPFMFRIIPADSSILDKQLDLISNGNIVWSDYGLLSLAKTSSLYMKYNSEHQAPYWRGAIW 704

  Fly   768 ININYLAAKALHHYGKIDGPNAALARQIYAELRDNLVGNILRQYKRSGYLWEQYDDTSGEGKGCN 832
            :|:||:...:||||..:|||..:.||.||.|||.||:.|::|.|.::|.:||.||.|.|.|:|..
plant   705 MNMNYMILSSLHHYSTVDGPYNSKARTIYEELRSNLIRNVVRNYDQTGIIWEHYDQTKGTGEGAR 769

  Fly   833 PFTGWTATVVLLMAEQF 849
            .||||:|.::|:|:|::
plant   770 VFTGWSALILLIMSEEY 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GCS1	NP_001245621.1	Glyco_hydro_63N	104..283	CDD:293528	71/183 (39%)
GCS1	NP_001245621.1	Glyco_hydro_63	352..847	CDD:281228	230/510 (45%)
AT1G24320	NP_173842.2	Glyco_hydro_63N	46..>200	CDD:293528	67/159 (42%)
AT1G24320	NP_173842.2	Glyco_hydro_63	285..784	CDD:281228	230/510 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	492	1.000	Domainoid score	I79
eggNOG	1	0.900	-	-		E1_KOG2161
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4593
Inparanoid	1	1.050	600	1.000	Inparanoid score	I220
OMA	1	1.010	-	-		QHG53903
OrthoDB	1	1.010	-	-		D278028at2759
OrthoFinder	1	1.000	-	-		FOG0004064
OrthoInspector	1	1.000	-	-		otm2941
orthoMCL	1	0.900	-	-		OOG6_103455
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2818
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740