DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34348 and tmem68

DIOPT Version :9

Sequence 1:	NP_001096954.1	Gene:	CG34348 / 32072	FlyBaseID:	FBgn0085377	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001039214.1	Gene:	tmem68 / 734073	XenbaseID:	XB-GENE-940824	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	324	Identity:	160/324 - (49%)
Similarity:	216/324 - (66%)	Gaps:	27/324 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LENLYKTLHSLLSSYID-LDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMR 67
            |||        |..|:: :||.||::   ||||:.|:||:..|..:|:|.|.|.:|| |:..:..
Frog    30 LEN--------LEDYLNYVDYLLWVF---TPLIIVFILPVFIVIFLYLSILFLHVYK-HKNELKE 82

  Fly    68 AVQGDRNFWRVGRKIVAAIWDAHARIYHGYEVIGLENVPQEGPALIVYYHGAIPIDMYYLNSRML 132
            |.  ..:.|...||.:|.:||.||.|:||||:.||||:|.:|||||||||||:|:|.||..::::
Frog    83 AY--SNSIWDGARKTLATLWDGHATIWHGYELYGLENIPDDGPALIVYYHGALPVDYYYFVAKVI 145

  Fly   133 LQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYY 197
            |::.|..:::||.||||:||:..:.:.|.|..|..:.||..|..|:|||:|||||.||.|.|..|
Frog   146 LRKGRTCHSVGDHFLFKIPGFKPLLDLFGVIHGPKEECVKALTSGHLLAVSPGGVREALFSDESY 210

  Fly   198 ELLWRNRVGFAKVAIEAKAPIIPCFTQNLREGFRQVG---IFRTFFMRLYNKVRIPVYPIYGGFP 259
            .|:|..|.|||:|||:||.||||.||||:|||||.:|   :||.    :|.:.:||:.|||||||
Frog   211 TLMWGKRTGFAQVAIDAKVPIIPMFTQNVREGFRSLGGLWLFRW----IYERFKIPLVPIYGGFP 271

  Fly   260 VKFRTYLGKPIPYDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFRRRVRRKEE 323
            ||||||||.||.||.|:|..:|..|...||..||.:||::||:|..|||:|   |.|  |:|||
Frog   272 VKFRTYLGDPIQYDPNITAVELAQKTKCAIHSLIEKHQKVPGNIFRALLER---FDR--RQKEE 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34348	NP_001096954.1	PlsC	47..271	CDD:223282	117/226 (52%)
CG34348	NP_001096954.1	LPLAT_MGAT-like	90..298	CDD:153249	115/210 (55%)
tmem68	NP_001039214.1	LPLAT_MGAT-like	103..310	CDD:153249	115/210 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4551
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12440
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2569
OMA	1	1.010	-	-		QHG48349
OrthoDB	1	1.010	-	-		D1558547at2759
OrthoFinder	1	1.000	-	-		FOG0006589
OrthoInspector	1	1.000	-	-		oto105173
Panther	1	1.100	-	-	LDO	PTHR22753
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3387
SonicParanoid	1	1.000	-	-		X4832
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110