DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34348 and AGPAT5

DIOPT Version :9

Sequence 1:	NP_001096954.1	Gene:	CG34348 / 32072	FlyBaseID:	FBgn0085377	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_060831.2	Gene:	AGPAT5 / 55326	HGNCID:	20886	Length:	364	Species:	Homo sapiens

Alignment Length:	174	Identity:	34/174 - (19%)
Similarity:	58/174 - (33%)	Gaps:	67/174 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 VSILRDGNLLAISPGGVYEAQFGDHYYELLW---------RNRVGFAKVAIEAKAPIIPCFTQNL 226
            |.||..|:|.......:|.|   :|...:.|         :|.:|..:..              |
Human    72 VQILLYGDLPKNKENIIYLA---NHQSTVDWIVADILAIRQNALGHVRYV--------------L 119

  Fly   227 REGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFPV-------------KFRTYL--GKPI-----P 271
            :||.:.:.::..:|.:            :||..|             |.::|:  |.|:     |
Human   120 KEGLKWLPLYGCYFAQ------------HGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFP 172

  Fly   272 YDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFR 315
            ......|:  |.||.:|.:....|..       ||:|..:.|.|
Human   173 EGTRYNPE--QTKVLSASQAFAAQRG-------LAVLKHVLTPR 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34348	NP_001096954.1	PlsC	47..271	CDD:223282	22/128 (17%)
CG34348	NP_001096954.1	LPLAT_MGAT-like	90..298	CDD:153249	29/155 (19%)
AGPAT5	NP_060831.2	PlsC	34..281	CDD:223282	34/174 (20%)
		LPLAT_LCLAT1-like	63..263	CDD:153252	34/174 (20%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q9D517	93..98		1/4 (25%)
		Acyltransf_C	258..318	CDD:292694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900