Protein Alignment Kap3 and kifap3a

DIOPT Version :10

• Sequence 1: NP_727512.3
• Gene: Kap3 / 32071
• FlyBaseID: FBgn0028421
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_001004644.1
• Gene: kifap3a / 447906
• ZFINID: ZDB-GENE-040912-74
• Length: 789
• Species: Danio rerio
• Alignment Length: 936
• Identity: 380/936 - (40%)
• Similarity: 548/936 - (58%)
• Gaps: 177/936 - (18%)

  Fly    98 DDAKFIKKRWKGGSIEPHPTDKALIVNYQLEATVFGEPNNPMIEEKKHCQKIIRLRSLNAKTDPA 162
            |||:::|:::||||::.|||:|||:|.|::|||:.||..:||:.|:|.|||||||:|||:.||.|
Zfish     4 DDARYLKRKYKGGSLDVHPTEKALVVQYEVEATILGEMGDPMLGERKECQKIIRLKSLNSNTDIA 68

  Fly   163 ALAREVVEKCDLIHKSQLNDVEQIIFYLKNRKDNASNDIPDNNTHSRRSAALHTSHTRSSARSHS 227
            :|||:|||:|.||..|:|.:|||::|||:|||.:|                      ....:...
Zfish    69 SLARKVVEECRLISPSRLPEVEQLLFYLQNRKKSA----------------------EKKEKKQI 111

  Fly   228 SVAAMTSSTGSGGGSTGASNGVSNALSAATPTADVSINNIDEYVELLYEELGERIRGSAMILQMA 292
            ....:|...|                  .....:.:|||||:|||||||::.|:|||:.:||.:|
Zfish   112 KPRDLTPFEG------------------MELDEEANINNIDDYVELLYEDIPEKIRGATLILHLA 158

  Fly   293 RNPDNLEELEKNEACLSALSRVLREDWRKSLDLSTNIIYIFFCFSTYTKFHPLIVQYKIGSLCMD 357
            |||||||||.:||..|.||:|||||||::|:||:|.|||||||||::::||.||..||||:|||.
Zfish   159 RNPDNLEELLQNETALGALARVLREDWKQSVDLATTIIYIFFCFSSFSQFHGLITHYKIGALCMS 223

  Fly   358 VIDYELRRYETMRNELDVRKQPNGSSTPHSAKASKEKLNRSTDDFLDIMNEEKPKEMEPPRRRIP 422
            :|::||:||:..::||                   :|..::.||  |..|:...||.|...::
Zfish   224 IIEHELKRYDLWQDEL-------------------QKKKKAGDD--DPDNQNLKKEYEKALKK-- 265

  Fly   423 ELKQRPKSGNWSSFHGSMSSSLIKSQILNSSYHESLCAGGSPGGDTPAVPAEQKAQSNESLDRND 487
                         :||.::
Zfish   266 -------------YHGLLT---------------------------------------------- 271

  Fly   488 PKVKKEEIDRLNKQLKIFAKKQEQLLRVAFYLLLNMAENVKLEEKMRRKHIVKMLVKALDRQNID 552
                                |||||||||.|||||::|:.:.|.|||.|:||.:|||.|||.:.:
Zfish   272 --------------------KQEQLLRVALYLLLNLSEDTRTELKMRNKNIVHLLVKTLDRDSEE 316

  Fly   553 LLMLVSTFLKKLSIVGDNKDEMGALNIVAKLPRLFQSTHTDLVQVTLKLVFNLSFDGGLRRKMIA 617
            ||:||.:|||||||..:||::|..:..|.||.:|....|.||:.|||:|:.|||||..||.||:.
Zfish   317 LLVLVVSFLKKLSIFLENKNDMAEVVTVEKLAKLVPCEHEDLLNVTLRLLLNLSFDTSLRSKMVQ 381

  Fly   618 AGYLPMLVMFINDEKHHGIAVKILYHMSLDDKVKGMFTQTECVQMATDAIILNLNVKVDLDLIAL 682
            |..||.|...:.||....||::||||:|:||:.|.||..|:|:......:......::|.:||:.
Zfish   382 ADLLPKLTSMLGDEAQRQIAMRILYHISMDDRFKSMFAYTDCIPQVMKMLFDCGEERIDAELISF 446

  Fly   683 CINLSLNRRNAQIMVEGQRLHSLMDRAFKYQDALLMKLLRNLSQHE--SLQLQFIDYVGDLARIL 745
            ||||:.||||.|||.||..|..||.||.|.:|.|:||::||:|||:  |..| |||||||||..:
Zfish   447 CINLAANRRNTQIMCEGNGLKMLMKRALKLKDPLMMKMIRNISQHDGPSKNL-FIDYVGDLAAQI 510

  Fly   746 TICDDEAFIVECLGILGNLALTDLDYSQILQNFQLIPWIRQILLPCARMDDLVLDTIVYLGTCAC 810
            .:.::|.|::||||.|.||.:.|||:..:|:.:.|:|:::..|:|.:..|||:|:.::.:||.:.
Zfish   511 GLKEEEEFVIECLGTLSNLTIPDLDWELVLKEYNLVPYLKDHLIPGSAEDDLILEVVIMIGTVSM 575

  Fly   811 DELCALLFCRAKVVISLIELLKAKQEDDEIVLQIIFVFQQILRHESTREYMIKETESAAYLIDLM 875
            |:.||::..::.::.:|||||.|:|||||.|.||::||.|::.|::||:.:||||::.|||||||
Zfish   576 DDSCAVMLAKSGIIPALIELLNAQQEDDEFVCQIVYVFYQMVFHQATRDVIIKETQAPAYLIDLM 640

  Fly   876 HDKNEEIRKVCDYCLDIIAISDSEWAKRIKLEKFRNHNSQWLCMVESQQ-DQDNEQDYADQEDEC 939
            ||||.|||||||..|||||..|.||.|:|:.||||.||||||.|||::| |:.....|.|
Zfish   641 HDKNAEIRKVCDNTLDIIAEYDVEWGKKIQSEKFRWHNSQWLEMVENRQMDEAEPFMYGD----- 700

  Fly   940 DNDLDTYLRS-EYLDNCDLYNDNADNDSNSN--------SNHSNNN-------PASPAMSTY--- 985
              |.:.:|:: :.|:..||:. :||....::        :|:.|.:       |:|.....|
Zfish   701 --DGEPFLQNGDILERPDLFY-SADGIIPADGAISPEFFTNYQNGDLLGQQGFPSSSLTDGYGQT 762

  Fly   986 ----SRPLSTYRRSQDLDDLYNMTSS 1007
                :||.:.|....|....|..|:|
Zfish   763 GVNSARPATAYGFRPDEQFYYGYTAS 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap3	NP_727512.3	KAP	107..957	CDD:253396	360/853 (42%)
kifap3a	NP_001004644.1	KAP	13..717	CDD:253396	360/853 (42%)