Protein Alignment Kap3 and kap-1

DIOPT Version :9

• Sequence 1: NP_727512.3
• Gene: Kap3 / 32071
• FlyBaseID: FBgn0028421
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_001367740.1
• Gene: kap-1 / 176041
• WormBaseID: WBGene00002182
• Length: 713
• Species: Caenorhabditis elegans
• Alignment Length: 873
• Identity: 232/873 - (26%)
• Similarity: 394/873 - (45%)
• Gaps: 212/873 - (24%)

  Fly   111 SIEPHPTDKALIVNYQLE------ATVFGEPNNPMIEEKKHCQKIIRLRSLNAKTDPAALAREVV 169
            ||:.||:|:|:||.::..      .::....::..:|...| ||||.|:.::...|..||:..::
 Worm     5 SIDAHPSDQAIIVRFEQSPSSSAGISIKKRASSANVESLGH-QKIIHLKEMSLDVDIRALSNVIL 68

  Fly   170 EKCDLIHKSQLNDVEQIIFYLKNRKDNASNDIPDNNTHSRRSAALHTSHTRSSARSHSSVAAMTS 234
            :||..|..:..:.:||::||::.|                       .:.|.||||.||.|
 Worm    69 QKCLFIPATSRSQLEQVLFYIQKR-----------------------GNQRISARSRSSSA---- 106

  Fly   235 STGSGGGSTGASNGVS-NALSAATPTADVSINNIDEYVELLYEELG-ERIRGSAMILQMARNPDN 297
                          || :.....:||....:..||||:|..|.|.. |:.:|:..:.::::||.|
 Worm   107 --------------VSFDRRPIHSPTISAELGKIDEYIECFYGETSVEKNKGAVALYELSKNPQN 157

  Fly   298 LEELEKNEACLSALSRVLREDWRKSLDLSTNIIYIFFCFSTYTKFHPLIVQYK---IGSLCMDVI 359
            |.:|..||..:.||:||.||||:|..::.|||:.:|...|.::..|.:::.:|   ||:||::.:
 Worm   158 LTQLVNNETLMMALARVFREDWKKHFEVGTNIMNLFVNISKFSCLHGILLHHKACMIGTLCVNAM 222

  Fly   360 DYELRRYETMRNELDVRKQPNGSSTPHSAKASKEKLNRSTDDFLDIMNEEKPKEMEPPRRRIPEL 424
            ::|.:||                                  ||
 Worm   223 EHETKRY----------------------------------DF---------------------- 231

  Fly   425 KQRPKSGNWSSFHGSMSSSLIKSQILNSSYHESLCAGGSPGGDTPAVPAEQKAQSNESLDRNDPK 489
                    |.                                      ||.|....|:|
 Worm   232 --------WI--------------------------------------AEMKKTDQETL------ 244

  Fly   490 VKKEEIDRLNKQLKIFAKKQEQLLRVAFYLLLNMAENVKLEEKMRRKHIVKMLVKALDRQNIDLL 554
                      ::||...:||..||......|.|:|.::.:|.||.|:::|.:|||.|...:....
 Worm   245 ----------RKLKTAIRKQAMLLAACVTFLTNLATDISVELKMVRRNLVALLVKCLQMSSESTS 299

  Fly   555 MLVST---FLKKLSIVGDNKDEMGALNIVAKLPRLFQSTHTDLVQVTLKLVFNLSFDGGLRRKMI 616
            .|.:.   ||.||||..:||..|.....:.||.:||.....:|.:..:.|:||.|||.....||:
 Worm   300 SLTTATIKFLLKLSIFDENKIVMEQNGTIEKLLKLFPIQDPELRKAVIMLLFNFSFDSKNLPKMV 364

  Fly   617 AAGYLPMLVMFINDEKHHGIAVKILYHMSLDDKVKGMFTQTECVQMATDAIILNLNVKVDLDLIA 681
            ..|.:|.:...::.:..   |:.::|.:|.:|..|.|...|:.:::....::.....:|..   |
 Worm   365 NGGLVPHMASLLDSDTK---ALNMMYLLSCNDDAKAMLAYTDAIKLLMKDVLSGTGSEVTK---A 423

  Fly   682 LCINLSLNRRNAQIMV--EGQRLHSLMDRAFKYQDALLMKLLRNLSQHE-SLQLQFIDYVGDLAR 743
            :.:|:.|.:||||::.  .||.|..||:.:...:|.:|:|::|.:|.|| :.|..|:.::..|
 Worm   424 VLLNICLEKRNAQLVCGQRGQGLDLLMEMSINSRDLMLIKVVRAISSHEGATQNMFLKWIETL-- 486

  Fly   744 ILTICDDE---------AFIVECLGILGNLALTDLDYSQILQNFQLIPWIRQIL---------LP 790
             :.|..:|         :|.:||:|.:..|.:.  .:::|:|:..|:||::..|         :.
 Worm   487 -IGIAKNEGADNSESKSSFGLECMGTVAELKVA--PWAKIIQSENLVPWMKTQLQEGIDESEEVT 548

  Fly   791 CAR-MDDLVLDTIVYLGTCACDELCALLFCRAKVVISLIELLKAKQEDDEIVLQIIFVFQQILRH 854
            ..| :..|.|..::..||.|.....|.|.  |.::.:.::||::.|.|||.|:|:::||.|.|:|
 Worm   549 VLRDIKPLQLQIVIACGTMARQLDAARLL--APLIDTFVQLLQSCQIDDEFVVQLLYVFLQFLKH 611

  Fly   855 -ESTREYMIKETESAAYLIDLMHDKNEEIRKVCDYCLDIIAISDSEWAKRIKLEKFRNHNSQWLC 918
             |.:...|.:::...|::||||||.|..:|:|||..|.|:.....||||||..|:|:.||:|||.
 Worm   612 KELSARLMTQDSALGAHMIDLMHDANAVVREVCDNALLIMGEHSKEWAKRIAGERFKWHNAQWLE 676

  Fly   919 MVESQQDQDNEQDYADQEDECDNDLDTY 946
            |||  :|.....||.|::...|...|.|
 Worm   677 MVE--RDDSEFVDYDDEDFGADLKFDHY 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap3	NP_727512.3	KAP	107..957	CDD:253396	232/873 (27%)
		ARM	531..632	CDD:237987	33/103 (32%)
		ARM	786..894	CDD:237987	39/118 (33%)
kap-1	NP_001367740.1	KAP	5..693	CDD:253396	229/862 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159472
Domainoid	1	1.000	207	1.000	Domainoid score	I1684
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7799
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.993157	Normalized mean entropy	S3709
OMA	1	1.010	-	-		QHG56928
OrthoDB	1	1.010	-	-		D247183at33208
OrthoFinder	1	1.000	-	-		FOG0006181
OrthoInspector	1	1.000	-	-		oto18749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15605
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3383
SonicParanoid	1	1.000	-	-		X4460
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940