DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gapvd1 and rabgef1l

DIOPT Version :9

Sequence 1:	NP_572704.1	Gene:	Gapvd1 / 32070	FlyBaseID:	FBgn0030286	Length:	1712	Species:	Drosophila melanogaster
Sequence 2:	NP_957235.1	Gene:	rabgef1l / 393915	ZFINID:	ZDB-GENE-040426-813	Length:	470	Species:	Danio rerio

Alignment Length:	230	Identity:	63/230 - (27%)
Similarity:	113/230 - (49%)	Gaps:	27/230 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1502 LEQFQAE----FAQLRASDERV------------ELTEEFVESLLQELRSSADLQDEWQVDAARV 1550
            |:.||..    |.|..|..|.:            :..::|.:|:.:.|:::.....| .|:....
Zfish   139 LKPFQRPGYDIFKQCHAFAENIAHKKVVGCEDLSDSVQDFYQSMSEYLQTNFKGSPE-VVETVME 202

  Fly  1551 AIERMLLEQMYEQVMFPNEDADVSRDEVLSAHIGKLQRFVHPAHPA-LCI-AQEYLGEAPWTF-- 1611
            .:||.::.::|||:..|:...|..:|..:...|    |.:|....| ||: ..|.:.:...:.
Zfish   203 EVERYVMGRLYEQLFCPDHTDDEKKDLTVQKRI----RALHWVSIAMLCVPLDEQIPKVSDSVER 263

  Fly  1612 AQQQLCHMAAYKTPREKLQCIINCISSIMSLLRMSSGRVPAADDLLPVLIYVVIMANPPYLLSTV 1676
            |:..|.::.:.|.|:|||.|:..|...|::.::.|.....:|||.||.|:|:::.||||.|.|.:
Zfish   264 AKTDLINLDSKKVPKEKLACVTRCSKHILTAIQGSKKAAASADDFLPALVYIILKANPPRLHSNI 328

  Fly  1677 EYIS--CFLGKKLEGEDEFYWTLFGSVVKFIKTMD 1709
            :||:  |...:.:.|||.:|:|.....|.||:.:|
Zfish   329 QYITRYCNPSRLMSGEDGYYFTNLCCAVSFIEKLD 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gapvd1	NP_572704.1	RasGAP_RAP6	90..460	CDD:213331
Gapvd1	NP_572704.1	VPS9	1609..1709	CDD:280383	35/103 (34%)
rabgef1l	NP_957235.1	zf-A20	17..40	CDD:280010
rabgef1l	NP_957235.1	VPS9	261..363	CDD:280383	35/101 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2319
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820