DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gapvd1 and LOC100498468

DIOPT Version :9

Sequence 1:	NP_572704.1	Gene:	Gapvd1 / 32070	FlyBaseID:	FBgn0030286	Length:	1712	Species:	Drosophila melanogaster
Sequence 2:	XP_031747412.1	Gene:	LOC100498468 / 100498468	-ID:	-	Length:	477	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	70/304 - (23%)
Similarity:	128/304 - (42%)	Gaps:	55/304 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1455 HRQQLLLRSEQ-----LEQLEARLR-----------GEARSSQRCL----LQALVRMYLAWSRQQ 1499
            |...|.::||:     |.|.|...|           ..::||.|..    :.|..|.::.||..:
Frog    86 HTGTLFMKSERENTSDLGQNENTARVVTINTDTMYAQHSQSSYRYFPTTDVTADPRCFIPWSSLE 150

  Fly  1500 EKLEQFQAEFAQLRASDERVELTEEFVESLLQELRSSADL---------QDEWQVDAARVA---- 1551
            ...::..::|.:.....|..:|..: ..:|:|.|:::.:|         ||.:.    |:|
Frog   151 SMAKRDFSDFLKALRRPEAQQLNAQ-CTNLIQRLQNAKNLTPNTMGEQIQDFYH----RIADQFP 210

  Fly  1552 -------------IERMLLEQMYEQVMFPNEDADVSRDEVLSAHIGKLQRFVHPAHPALCIAQEY 1603
                         ||::::.::|..|...:...|..:|.:|...|..| ::|.|....:.:.:..
Frog   211 DHMTEERGYFLDNIEKLVMTRLYRSVFCLDGSTDEQKDLLLQRRIKSL-KWVTPKMLQVPLDETI 274

  Fly  1604 LGEAPWTF-AQQQLCHMAAYKTPREKLQCIINCISSIMSLLRMSSGRVPAADDLLPVLIYVVIMA 1667
            :....||. |...:..|.:.:.|::||.|:....:.:...:|.|......|||.|..|||:.:.|
Frog   275 VEVKDWTLSAVTAMLEMDSRRAPQDKLTCVSRASNCLFKSIRASKKDPATADDFLSCLIYITLRA 339

  Fly  1668 NPPYLLSTVEYISCFLG--KKLEGEDEFYWTLFGSVVKFIKTMD 1709
            |||.|.|.:||::.|..  :...||..:.:|.....|.||:.:|
Frog   340 NPPRLFSNLEYLTRFCNPVRLTTGEWGYCFTNLCCAVSFIENLD 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gapvd1	NP_572704.1	RasGAP_RAP6	90..460	CDD:213331
Gapvd1	NP_572704.1	VPS9	1609..1709	CDD:280383	32/102 (31%)
LOC100498468	XP_031747412.1	zf-A20	46..67	CDD:396357
		DUF5601	175..233	CDD:407982	10/62 (16%)
		VPS9	283..383	CDD:366977	30/99 (30%)
		Lebercilin	399..>462	CDD:406132
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920