Protein Alignment HOXA11 and Abd-B

DIOPT Version :10

• Sequence 1: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 96/329 - (29%)
• Similarity: 139/329 - (42%)
• Gaps: 93/329 - (28%)

Human    21 YVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSA 85
            :::.|....||.  .|||:|  :....||||.|.|..:..     |:.|.
  Fly   158 HLTSPHHQQLPQ--QQTPNS--VASGASSNLQQQQQQQNA-----AVAPG--------------- 198

Human    86 EELVHRDCLQAPSAAGV-PGDVLA-KSSANV------YHHPT----PAVSSNFYSTVGRN----G 134
                 :..:.||:.|.| |..|.: |...|:      .|.|.    |...::..:.|.|:    .
  Fly   199 -----QTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWA 258

Human   135 VLPQAFDQFFETAYGTPENLASSDYPGDK---SAEKGP---PAATATSAAAAAAATGAPATSSSD 193
            ...:.|:|.:.:.|...:::.:..||..:   ....||   |..|.::|||||....|.
  Fly   259 YNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAE------ 317

Human   194 SGGGGGCRETAAAAEE-----KERRRRPESSSSP----------ESSSGHTEDKAGGSSGQRT-- 241
                   |..:|||.:     ......|.:.|||          .||||.:...:.|:.|..|
  Fly   318 -------RHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPN 375

Human   242 ------------RKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRM 294
                        ||||.||:|:|..|||:||.|:.|::|:||.:|:|.|.||:||||||||||||
  Fly   376 PGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRM 440

Human   295 KEKK 298
            |.||
  Fly   441 KNKK 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	31/143 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		30/126 (24%)
		Homeodomain	242..298	CDD:459649	36/55 (65%)
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	36/55 (65%)