Protein Alignment HOXA11 and lbe

DIOPT Version :10

• Sequence 1: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 75/341 - (21%)
• Similarity: 128/341 - (37%)
• Gaps: 86/341 - (25%)

Human    35 PQTPSSRPMTYSYSSNLPQVQPVREVTF----------REYAIEPATKWHPRGNLAHCYSAEELV 89
            |..||:.|...:..:....::.|:..:.          ||.::.|.    |..||....::..:
  Fly   109 PSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPP----PNANLLAPPASRPI- 168

Human    90 HRDCLQAPSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQ----------FF 144
                  |||     |.:|...:..:..||..|.:....|     |.:.:.:|.          |.
  Fly   169 ------APS-----GGLLQPRTEPLDVHPAAAAAMLLPS-----GQIVRPWDHLLGPTMPVRPFI 217

Human   145 ETAYGTPENLASSDYPGDKSAEKGPPAA----TATSAAAAAAATGAPATS--SSDSGGGGGC--- 200
            .:|....|...:.||...........|.    ...:.|..|:..|:...|  ||.|.|...|
  Fly   218 PSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSP 282

Human   201 RE--------TAAAAEEKERRRRPESSSSPESSSGHT----------------EDK------AGG 235
            |:        |...:||.::::..|..:....|:|.|                :||      :..
  Fly   283 RQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNR 347

Human   236 SSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEK--- 297
            ...::.||.|..:|.:||.|||:.|.:..|::...|.:::..|.|::.||..||||||.|:|
  Fly   348 PQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDI 412

Human   298 ---KINRDRLQYYSAN 310
               |.:.|.::.:||:
  Fly   413 EELKKDFDSVKVFSAH 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	24/137 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		24/130 (18%)
		Homeodomain	242..298	CDD:459649	24/61 (39%)
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	23/55 (42%)