Protein Alignment HOXA11 and unpg

DIOPT Version :10

• Sequence 1: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 83/317 - (26%)
• Similarity: 131/317 - (41%)
• Gaps: 69/317 - (21%)

Human     7 GPCSSNMYLPSCTYYVSGPDFSSLP--SFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEP 69
            |.|    ||||..   :|...:..|  ...||.|...|.|::....||...| ..:..|.....|
  Fly   106 GGC----YLPSSP---AGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLP-HPLDTRFLPFNP 162

Human    70 ATKWHPRGNLAHCYSAEELVHRDC---------LQAPSAAGVPGDVLAKSSANVYHHPTPAVSSN 125
            |.......:|::...| ||:::|.         ||..:|||...:..|.........|||..:
  Fly   163 AAAGVAPTDLSYRRLA-ELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQA-- 224

Human   126 FYSTVGRNG-------VLPQAFDQFFETAYGTPENLASS----DYPG--DKSAEKGPPAATATSA 177
             :|:..::|       .|....|:.||.:..:..:::.:    :|.|  |||..     ...|::
  Fly   225 -HSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRN-----GAYTNS 283

Human   178 AAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTR 242
            .:...:....|.|..:.||.||                       :.|.|:     |.||..::|
  Fly   284 DSEDCSDDEGAQSRHEGGGMGG-----------------------KDSQGN-----GSSSNSKSR 320

Human   243 KKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKI 299
            ::|..:|..|:.||||||....|::..:|.|::..|.|::.||||||||||.|.|::
  Fly   321 RRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	32/145 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		18/97 (19%)
		Homeodomain	242..298	CDD:459649	26/55 (47%)
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	24/51 (47%)