Protein Alignment HOXA11 and CG32532

DIOPT Version :10

• Sequence 1: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 56/214 - (26%)
• Similarity: 84/214 - (39%)
• Gaps: 63/214 - (29%)

Human   103 PGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPG-DKSAE 166
            |...|.|||::..:|.....|:            |:.|...:.   |.|.       || |.|:.
  Fly   399 PITTLEKSSSSSLNHQRKCSST------------PEDFSALYS---GLPT-------PGMDSSSH 441

Human   167 KGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSS----------S 221
            ...||.|             |.:..||.         ..:||...::.:||.:|          |
  Fly   442 HHTPAHT-------------PPSRLSDH---------TISAEGAFKKLKPEPNSGLSTVSAGITS 484

Human   222 PESS-------SGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLN 279
            |.|.       :|||...|...:..| |:.|..:|:.|:.|||..|..|.|.:...|.:|:|...
  Fly   485 PGSGLSSLSQHAGHTPTTASCPTPAR-RRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTK 548

Human   280 LTDRQVKIWFQNRRMKEKK 298
            |.:.::::||||||.|.:|
  Fly   549 LNEARIQVWFQNRRAKYRK 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	11/49 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		24/109 (22%)
		Homeodomain	242..298	CDD:459649	21/55 (38%)
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	21/55 (38%)