Protein Alignment HOXA11 and vnd

DIOPT Version :10

• Sequence 1: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 74/296 - (25%)
• Similarity: 110/296 - (37%)
• Gaps: 78/296 - (26%)

Human    74 HPRGNLAHCYSAEELVHRDCLQAPSAAG---------VPGDVLAKSSANVYHHPTPAVSSNFYST 129
            |.....||..::    |.....|..|||         .||....:.|:  |||    ::......
  Fly   338 HANAAAAHLLAS----HNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSS--YHH----MAQTMLQH 392

Human   130 VGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAE----------------KGPPAATATSAA 178
            .||:..:.:      ...||| :..||.|.....::|                .|...:.:.||.
  Fly   393 SGRSAWIKE------NELYGT-QQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSAD 450

Human   179 AAAAATGAPATS---SSDSGGGGGCRETAAAAEEKERRRRPESSSSPE------SSSGHTE---- 230
            :.|.:.|....:   ||.:|..||. .||.|...........::.|.:      :.|||.:
  Fly   451 SDALSVGDALHTLHGSSGNGSAGGA-PTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNE 514

Human   231 ----------DKAGGSSG----------QRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLS 275
                      |.|.||.|          .:.||:|..:||.|..||||.|....|::..:|..|:
  Fly   515 DGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLA 579

Human   276 RMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANP 311
            .::.||..||||||||.|.|.|:...::  .|..:|
  Fly   580 SLIRLTPTQVKIWFQNHRYKTKRAQNEK--GYEGHP 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	19/87 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		28/140 (20%)
		Homeodomain	242..298	CDD:459649	26/55 (47%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	26/55 (47%)