Protein Alignment Ir10a and grik4

DIOPT Version :10

• Sequence 1: NP_001096949.1
• Gene: Ir10a / 32067
• FlyBaseID: FBgn0083979
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 692
• Identity: 134/692 - (19%)
• Similarity: 254/692 - (36%)
• Gaps: 189/692 - (27%)

  Fly     6 TVFLLFMLDLKTLNLTRLNGLLVEPTRDLPQLELWLRAGSDHQDAENPYVQWFLLRTEIPLSIVT 70
            :|:..::|.....:|.||:.|..:....:         |....:..:|:.|.|:|..
Zfish   238 SVYYTYILTSLEFSLLRLDDLADQRVNIV---------GFSVFNRTHPFFQDFVLSL-------- 285

  Fly    71 YQENRYWMDD----PFGRRNLVLVMSLDQLLT------------NRGAAAPIQKASTFFYILADQ 119
               ||.|.::    ||....|...:..|.:.|            |.||.....|:|..:
Zfish   286 ---NRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNVGATQLSCKSSKIW------ 341

  Fly   120 DKDLSADEQLR---LEGSCRQLWTQHKVYN------RFFL-----TRDGVWIYDPFKRRDSAFGR 170
            :...|....||   |||     .|.|..:|      .:.|     :|||:             .:
Zfish   342 EHGTSLMNYLRMVELEG-----LTGHIEFNSKGQRSNYALRIMQNSRDGL-------------RQ 388

  Fly   171 LVRYYGSETLDKLLFRDMAGYPLRIQMFRSVYTRPEFDKETGLLTR-----VTGVD----FLVAQ 226
            :.:::..:.|.  :.|.:....:...:|.:..|.....:...::.|     :.|.|    |.| .
Zfish   389 IGQWHSEQGLS--MERKLPSLNVTDTLFNTTLTITTILENPYVMLRANHQELEGNDRYEGFCV-D 450

  Fly   227 MLRER---LNFTMLLQQPEKKYFGERSANGSYNGAIGSIIKDGLDICLTGFFV---KDYLV---Q 282
            ||:|.   |.|...::......:|...|||::.|.:|.:|....|:.:....:   ::.::   :
Zfish   451 MLKELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDFSK 515

  Fly   283 QYMDFTVAVYDDELCIYVPKASRIPQ--SILPIFAVGYDIWLGFVLTAF---ACALIWLTLRVIN 342
            .:|...:::      :|.....|.|.  |.|..|:.|  :|| |:|.|:   :|.| :|..|:..
Zfish   516 PFMTLGISI------MYRVHIGRRPGYFSFLDPFSPG--VWL-FMLLAYLAVSCVL-FLVARLTP 570

  Fly   343 ---------LKLRIVSLGNQHIVGQALGIMVDTWVVWVRLNLSHLPASYAERMFIGTLCLVSVIF 398
                     ||.|...|.||:.:|.:....|..   :::...:..|.:.:.|...|.....::|.
Zfish   571 YEWYNPHPCLKGRCSLLINQYSLGNSFWFPVGG---FMQQGSTIAPRALSTRCVSGVWWAFTLII 632

  Fly   399 GAIFESSLATVYIHPLYYKDINTM----QELDESGLKVVYKYSSM--ADDLFFSETSPLFASLNK 457
            .:.:.::||.       :..:..|    :.:|:...:...:|.:|  ...:.|.:.| .:.:..:
Zfish   633 ISSYTANLAA-------FLTVQRMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNS-RYQTYQR 689

  Fly   458 KLSWNRDLRADVI-----DEVARFRNKAGVSRYTSLILESSHFTLLRKIWVVPEC---------- 507
            ..::....:..|.     :.:||..|    |.| :.:|||:    :.:.:....|
Zfish   690 MWNFMYSKQPSVFVKSTEEGIARVLN----SNY-AYLLEST----MNEYYRQRNCNLTQIGGLLD 745

  Fly   508 PKYYTISYVMPRDSPWEDAVNALLLRFLNAGLIVKWIQDE--------KSWVDIKMRSNILEADA 564
            .|.|.|.  ||..|.:.|..:..:||          :|:|        |.|...|...   |.|.
Zfish   746 TKGYGIG--MPLGSVYRDEFDLAILR----------LQEENRLEILKRKWWDGGKCPK---EEDH 795

  Fly   565 ESELVRVLTIGDLQLAFYVVIGGNLLA-FLGFLAEHFRWKLQ 605
            .::.:.:..||.:   |.|::.|.|:| |:..|  .|.|.|:
Zfish   796 RAKGLGMENIGGI---FVVLVCGLLVAIFMAVL--EFVWMLR 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:473866	17/86 (20%)
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	38/208 (18%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	77/402 (19%)