DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir10a and Ir7a

DIOPT Version :9

Sequence 1:	NP_001096949.1	Gene:	Ir10a / 32067	FlyBaseID:	FBgn0083979	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	625	Identity:	121/625 - (19%)
Similarity:	234/625 - (37%)	Gaps:	133/625 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LRAGSDHQDAENPYVQWFLLRT---------------EIPLSIVTYQENRYWMDDPFGRRNLVLV 90
            |...::|:|.....:...:||:               |:|.|.|.:                 ||
  Fly    54 LTQDAEHRDERQEQLMTIILRSVGSEMALRTFQKPPAEVPASFVVF-----------------LV 101

  Fly    91 MSLDQLLTNRGAAAPIQKASTFFYILADQDKDLSADEQLRLEGSCRQLWTQHKVYNRFFLT--RD 153
            .|.....|.......|.....|.:::....:..|..|:|::.....:...:....|...||  ||
  Fly   102 NSAQAFNTLGFHFTDIHSTREFNFLILLTHRMSSRAERLQVLRDISRTCVRFHTSNVILLTEKRD 166

  Fly   154 GVWIYDPFKRRD-----SAFGRLVRYY-------GSE--TLDKLLFRDMAGYPLRIQMFRSVYTR 204
            ||.:...::..:     |....|:..|       |.|  :.:::|  .::|.||::    |.|..
  Fly   167 GVVLVYAYRLLNMDCDLSVNLELIDIYKNGLFRHGHEARSFNRVL--SLSGCPLQV----SWYPL 225

  Fly   205 PEF---------DKETGLLTRVTGVDFLVAQMLRERLNFTMLLQQPEKKYFGERSANGSYNGAIG 260
            |.|         .:|...:.|:||:|..:.::|....:|.:||::|             .|..:.
  Fly   226 PPFVSFIGNSSDPEERAQIWRLTGIDGELIKLLASIFDFRILLEEP-------------CNKCLS 277

  Fly   261 SIIKDGLDIC-----------LTGFFVKDYLVQQYMDFTVAVYDDELCIYVPKASR---IPQSIL 311
            ..|||....|           |.|.....:..:.:..||.:.:...|...:..:|:   :.|..:
  Fly   278 PDIKDDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAV 342

  Fly   312 PIFAVGYDIWLGFVLTAFACALI-WLTLRVINLKLRIVSLGNQHIVGQALGIMVDTWVVWVRLNL 375
            |...:   :||..|:::....|: |:..|::        .|...:...||.::  |.::...|..
  Fly   343 PFTVI---VWLALVVSSLLLVLVLWMRNRLV--------CGRSDLASHALQVL--TTLMGNPLEA 394

  Fly   376 SHLPASYAER-MFIGTLCLVSVIFGAIFESSLATVYIHPLYYKDINT-MQELDESGLKVV-YKYS 437
            ..||.|...| ::.|.|.|| ::...:::..|...:..| |:|.:.| :.||..|...:: .:|.
  Fly   395 RSLPRSSRLRILYAGWLLLV-LVLRVVYQGKLFDSFRLP-YHKPLPTEISELIRSNYTLINQEYL 457

  Fly   438 SMADDLFFSETSPLFASLNKKLSWNRDLRADVIDEVARFRNKAGVSRYTSLILESSHFTLLR--- 499
                |.:..|.:.|..:.:|.       |.|.|..:    .|.|....||||....::.::.
  Fly   458 ----DYYPRELTVLTRNGSKD-------RFDYIQGL----GKEGKFTTTSLIATMEYYNMMHWST 507

  Fly   500 -KIWVVPECPKYYTISYVMPRDSPWEDAVNALLLRFLNAGLIVKWIQDEKSWVDIKMRSNILEAD 563
             ::..:.|....|.:...:.|.|..:.|.:..:.:.|:||:|..::::    .|........|.|
  Fly   508 SRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVRE----FDACQYRKPFEED 568

  Fly   564 AESELVRVLTIGDLQLAFYVVIGGNLLAF-LGFLAEHFRW 602
            .|...:.:.:...|.....:.:...::|| |..|::...|
  Fly   569 YEVTPIPLDSFCGLYYISLIWLSAAVVAFILELLSQRIVW 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:304360	15/84 (18%)
		TM_PBP1_branched-chain-AA_like	315..>411	CDD:294309	20/97 (21%)
		Lig_chan	319..587	CDD:278489	55/275 (20%)
Ir7a	NP_572406.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010