Protein Alignment Ir10a and glr-8

DIOPT Version :10

• Sequence 1: NP_001096949.1
• Gene: Ir10a / 32067
• FlyBaseID: FBgn0083979
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 99/428 - (23%)
• Similarity: 183/428 - (42%)
• Gaps: 82/428 - (19%)

  Fly   223 LVAQMLRE---RLNFTMLLQQPEKKYFGERSANGSYNGAIGSIIKDGLDICLTGFFVKDYLVQQY 284
            :|.::|:|   |||.|..:.......:|| ..|||:.||.|.:::..:|: |.|..:.:|.....
 Worm    95 VVMEILKEIGKRLNLTYEILPALGSTWGE-YLNGSWTGAFGQLVRGEVDL-LAGGAIMEYDRSVI 157

  Fly   285 MDFTVAVYDDELCIYVPKASRIPQSILPIFA--VGYDIWLGFVLTAFACALIWLTLRVINLKLRI 347
            .|.|.....:...|.:....:.....|.|..  ..:::|   |:||   |:|.::        .:
 Worm   158 ADLTYPFQFEPTGIMIRSPEKYEDDTLLIVTEPFSWEVW---VITA---AVILIS--------GV 208

  Fly   348 VSLGNQHIVGQALGIMVDT-----WV---VWVRLNLSHLPASYAERMFIGTLCLVSVIFGAIFES 404
            :.|...:|:.:....|..|     ||   ::|:..|...|.|::.|:.:....|.|:...|.|..
 Worm   209 IFLVMTNIIRKVYEEMTVTPFESIWVFFSIFVQQGLPEQPRSWSCRVLVALWWLASITLSATFTG 273

  Fly   405 SLATVYI---HPLYYKDINTMQELDESGLKVVYKYSSMADDLFFSETSPLFASLNKKLSWNRDLR 466
            ||..::.   ..:.:::|:.:..|.:.|     |:..:.|:..|:.|..:..|   ||...|||.
 Worm   274 SLVALFAVDKTNVPFQNIDQLVRLVKQG-----KFEIVMDENSFTRTEMIARS---KLPVYRDLW 330

  Fly   467 AD-VIDEVARFRNKAGVSRYTSLILESSHFTLL-----RKIWVVPEC----------PKYYTISY 515
            .: :::...::.|  |::|..:.:..:..:.||     ...:...:|          |.|.:|..
 Worm   331 HEMIVNHKVKYVN--GIARGVAFVRANPGYALLGPMATLNFYAYSDCKVILFNDGILPVYLSIPL 393

  Fly   516 VMPRDSPWEDAVNALLLRFLNAGLIVKWIQDEKSWVDIKMRSNILEADAESELVRVLTIG----- 575
            |  ::|.:....:..:...:..|...|||.|.:|:|.::   .|.|.::       .|||
 Worm   394 V--KNSIYSPYFSTKIREMVERGFTQKWIADYRSYVAMQ---KINECNS-------TTIGPKSYL 446

  Fly   576 DL---QLAFYVVIGG---NLLAFLG-FLAEHFRWKLQK 606
            ||   |.||:|.:||   .|..|:| |:.:.||.|:.|
 Worm   447 DLKRAQGAFWVFLGGAGLGLALFVGEFIFKFFREKMTK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:473866	21/73 (29%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	76/356 (21%)