Protein Alignment Ir10a and gria2a

DIOPT Version :10

• Sequence 1: NP_001096949.1
• Gene: Ir10a / 32067
• FlyBaseID: FBgn0083979
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_005170953.1
• Gene: gria2a / 170450
• ZFINID: ZDB-GENE-020125-3
• Length: 893
• Species: Danio rerio
• Alignment Length: 644
• Identity: 137/644 - (21%)
• Similarity: 218/644 - (33%)
• Gaps: 170/644 - (26%)

  Fly    49 DAENPYVQWFLLRTEIPLSIVTYQENRYWMDDPFGRRNLVLVMSLDQLLTNRGAAAPIQKASTFF 113
            |.::|.|..|..|.|      ..:|..|...|...|....|.....|::|..            |
Zfish   259 DFDDPLVAKFDQRWE------ALEEKEYPGADSRIRYTSALTYDAVQVMTEA------------F 305

  Fly   114 YILADQDKDLSADEQLRLEGSC----RQLWTQHKVYNRFFLTRDGVWIYDPFKR----------R 164
            ..|..|..|:|....   .|.|    ...|.|            ||.|....|:          :
Zfish   306 RFLHKQRIDISRRGN---NGDCLANPAVPWAQ------------GVEIERALKQVRVDGLTGNIQ 355

  Fly   165 DSAFGRLVRY----------------YGSETLDKL------LF-RDMAGYPLRIQMFRSVYTRP- 205
            ...:||.|.|                |.:| :||:      || .|..|...:..:..::...|
Zfish   356 FDQYGRRVNYTVNVMELKNSGPVKIGYWNE-MDKMAVTKSDLFPNDTMGMENKTVIVTTILEAPY 419

  Fly   206 -EFDKETGLLT---RVTGVDFLVAQMLRERLNFTMLLQQPEKKYFGERSANGS-YNGAIGSIIKD 265
             ...|...|.|   |..|....:|..:.:...|...|:......:|.|.|... :||.:|.::..
Zfish   420 VMLKKNAELFTDNERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGARDAETKIWNGMVGELVYG 484

  Fly   266 GLDIC---LTGFFVKDYLVQQYMDFTVAVYDDELCIYVPKASRIPQSILP-IFA----VGYDIWL 322
            ..||.   ||...|:    ::.:||:.......:.|.:.|    ||...| :|:    :.|:||:
Zfish   485 KADIAVAPLTITLVR----EEVIDFSKPFMSLGISIMIKK----PQKSKPGVFSFLDPLAYEIWM 541

  Fly   323 GFVLTAFACALI-----------WLTLRVINLKLRIVSLGNQHIVGQALGIMVDTWV---VWVRL 373
            ..|......:::           |.|....:.:|......|:      .||....|.   .:::.
Zfish   542 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGQLGPSESTNE------FGIFNSLWFSLGAFMQQ 600

  Fly   374 NLSHLPASYAERMFIGTLCLVSVIFGAIFESSLA---TV--YIHPL-YYKDINTMQE-----LDE 427
            .....|.|.:.|:..|.....::|..:.:.::||   ||  .:.|: ..:|:....|     ||.
Zfish   601 GCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDA 665

  Fly   428 SGLKVVYKYSSMADDLFFSETSPLFASLNKKLSWNRDLRAD-------VIDEVARFRNKAGVSRY 485
            ...|..::.|.:|          ||..:     |.....|:       .::.|.|.|...|...|
Zfish   666 GSTKEFFRRSKIA----------LFDKM-----WQYMKSAEPSVFVKNTVEGVLRVRKSKGKYAY 715

  Fly   486 TSLILESSHFTLLRKIWVVPEC----------PKYYTISYVMPRDSPWEDAVNALLLRFLNAGLI 540
               :|||   |:...|.....|          .|.|.|:  .|:.|...:|||..:|:....||:
Zfish   716 ---LLES---TMNEYIEQRKPCDTMKVGGNLDSKGYGIA--TPKGSALRNAVNLAVLKLNEQGLL 772

  Fly   541 VKWIQDEKSWVDIKMRSNILEADAES-ELVRVLTIGDLQLAFYVVIGGNLLAFLGFLAE 598
            .|  ...|.|.|   :........|| |....|::.::...||:::||..||.|..|.|
Zfish   773 DK--LKNKWWYD---KGECGSGGGESKEKTSALSLSNVAGVFYILVGGLGLAMLVALVE 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:473866	16/77 (21%)
gria2a	XP_005170953.1	Periplasmic_Binding_Protein_type1	23..393	CDD:471960	34/167 (20%)
		PBP2_iGluR_AMPA	406..783	CDD:270433	86/418 (21%)