Protein Alignment Ir10a and Grik5

DIOPT Version :10

• Sequence 1: NP_001096949.1
• Gene: Ir10a / 32067
• FlyBaseID: FBgn0083979
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 497
• Identity: 108/497 - (21%)
• Similarity: 199/497 - (40%)
• Gaps: 96/497 - (19%)

  Fly   154 GVWIYDPFKRRDSAFGRLVRYYGSETLDKLLFRDMAGYPLRIQMFRS---VYTRPEFDKETGLLT 215
            |||    :..|..|.       .:.|||..|.:.:|...|.:.....   |..||.|...:| ..
Mouse   412 GVW----YSNRTLAM-------NATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSG-NE 464

  Fly   216 RVTG--VDFLVAQMLRERLNFTMLLQQPEKKYFGERSANGSYNGAIGSII-KDGLDICLTGFFV- 276
            |..|  ||.|  :.|.|.|.|...|:..|...:|....|||:.|.:|.:| :...|:.:..|.:
Mouse   465 RFEGFCVDML--RELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTIT 527

  Fly   277 --KDYLV---QQYMDFTVAVYDDELCIYVPKASRIPQ--SILPIFAVGYDIWLGFVLTAF---AC 331
              ::.::   :.:|...:::      :|.....|.|.  |.|..|:..  :|| |:|.|:   :|
Mouse   528 AEREKVIDFSKPFMTLGISI------LYRVHMGRKPGYFSFLDPFSPA--VWL-FMLLAYLAVSC 583

  Fly   332 ALIWLTLRVIN---------LKLRIVSLGNQHIVGQALGIMVDTWVVWVRLNLSHLPASYAERMF 387
            .| :|..|:..         |:.|...|.||:.:|.:|...|..   :::.....:|.:.:.|..
Mouse   584 VL-FLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGG---FMQQGSEIMPRALSTRCV 644

  Fly   388 IGTLCLVSVIFGAIFESSLATVYIHPLYYKDINTMQEL-DESGLK--VVYKYSSMADDLFFSETS 449
            .|.....::|..:.:.::||...........:.:..:| |::.::  .::..|:|.   ||..:.
Mouse   645 SGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMT---FFQNSR 706

  Fly   450 PLFASLNKKLSWNRDLRADVI-----DEVARFRNKAGVSRYTSLILESSHFTLLRKIWVVPEC-- 507
              :.:..:..::.:..:..|.     :.:||..|    ||| :.:|||:.....|::    .|
Mouse   707 --YQTYQRMWNYMQSKQPSVFVKSTEEGIARVLN----SRY-AFLLESTMNEYHRRL----NCNL 760

  Fly   508 --------PKYYTISYVMPRDSPWEDAVNALLLRFLNAGLIVKWIQDEKSWVDIKMRSNILEADA 564
                    .|.|.|.  ||..||:.|.:...:|:......:.  |...|.|...:...   |.|.
Mouse   761 TQIGGLLDTKGYGIG--MPLGSPFRDEITLAILQLQENNRLE--ILKRKWWEGGRCPK---EEDH 818

  Fly   565 ESELVRVLTIGDLQLAFYVVIGGNLLAFLGFLAEHFRWKLQK 606
            .::.:.:..||.:   |.|:|.|.::|....:.| |.|..::
Mouse   819 RAKGLGMENIGGI---FVVLICGLIIAVFVAVME-FIWSTRR 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:473866	19/80 (24%)
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	5/22 (23%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:473866	85/404 (21%)