Protein Alignment Ir10a and grik5

DIOPT Version :10

• Sequence 1: NP_001096949.1
• Gene: Ir10a / 32067
• FlyBaseID: FBgn0083979
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 706
• Identity: 144/706 - (20%)
• Similarity: 267/706 - (37%)
• Gaps: 176/706 - (24%)

  Fly    12 MLD--------LKTLNLTRLNGLLVEPTRDLPQLELWLRAGSDHQDAENPYVQWFLLRTEIPL-- 66
            |||        ||.:...:::.::::....:..|.|...:......|...|:   |...:.||
 Frog   196 MLDESNDPTPLLKEIRDDKVSTIIIDANATVSHLILKKASELGMTSAHYKYI---LTTMDFPLLS 257

  Fly    67 --SIVTYQEN-----RYWMDDPFGRRNLVLVMSLD-------QLLTNRGAAAPIQKASTFF---Y 114
              .||:.|.|     .|....||   .|..:.||:       :|.|..|   |...|:..|   :
 Frog   258 LEGIVSDQSNILGFSMYNSSHPF---YLEFLRSLNMSWRENCELSTYLG---PALSAALMFDAVH 316

  Fly   115 ILADQDKDLSADEQL---RLEGSCRQLWTQHKV----YNRFF----LT----------------- 151
            ::....::|:..:::   :|..|..|:| ||..    |.|..    ||
 Frog   317 VVVSAVRELNRSQEIGVKQLSCSTSQIW-QHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLR 380

  Fly   152 ---------RD-GVWIYDPFKRRDSAFGRL-VRYYGSETLDK--LLFRDMA--GYPLRIQMFRSV 201
                     |: |||    :..|..|.... :....||||:.  |:...:.  .|.:|...:||:
 Frog   381 ILEKAGDGHREIGVW----YSNRTLAMNATSLDLSTSETLENKTLVVTTILENPYMMRKSNYRSL 441

  Fly   202 YTRPEFDKETGLLTRVTGVDFLVAQMLRE---RLNFTMLLQQPEKKYFGERSANGSYNGAIGSII 263
            ....:::.             ..|:||.|   .|.|...::..|...:|....|||:.|.:|.:|
 Frog   442 SGNDQYEG-------------FCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGSWTGMVGELI 493

  Fly   264 KDGLDICLTGFFV---KDYLV---QQYMDFTVAVYDDELCIYVPKASRIPQ--SILPIFAVGYDI 320
            ....|:.:..|.:   ::.::   :.:|...:::      :|..:..|.|.  |.|..|:..  :
 Frog   494 NRKADLAVAAFTITAEREKVIDFSKPFMTLGISI------LYRVQMGRKPGYFSFLDPFSPA--V 550

  Fly   321 WLGFVLTAF---ACALIWLTLRVIN---------LKLRIVSLGNQHIVGQALGIMVDTWVVWVRL 373
            || |:|.|:   :|.| :|..|:..         |:.|...|.||:.:|.:|...|..   :::.
 Frog   551 WL-FMLLAYLAVSCVL-FLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGG---FMQQ 610

  Fly   374 NLSHLPASYAERMFIGTLCLVSVIFGAIFESSLATVYIHPLYYKDINTMQEL-DESGLK--VVYK 435
            ....:|.:.:.|...|.....::|..:.:.::||...........|.:..:| |::.::  .::.
 Frog   611 GSEVMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESADDLADQTNIEYGTIHG 675

  Fly   436 YSSMADDLFFSETSPLFASLNKKLSWNRDLRADVI-----DEVARFRNKAGVSRYTSLILESSHF 495
            .|:|.   ||..:.  :.:..:..::....:..|.     :.:||..|    ||| :.:|||:..
 Frog   676 GSTMT---FFQNSR--YQTYQRMWNYMNSKQPSVFVKSTEEGIARVLN----SRY-AFLLESTMN 730

  Fly   496 TLLRKIWVVPEC----------PKYYTISYVMPRDSPWEDAVNALLLRFLNAGLIVKWIQDEKSW 550
            ...|::    .|          .|.|.|.  ||..||:.|.:...:|:......:.  |...|.|
 Frog   731 EYHRRL----NCNLTQIGGLLDTKGYGIG--MPLGSPYRDEITLAILQLQENNRLE--ILKRKWW 787

  Fly   551 VDIKMRSNILEADAESELVRVLTIGDLQLAFYVVIGGNLLAFLGFLAEHFRWKLQK 606
            ...|...   |.|..::.:.:..||.:   |.|:|.|.::|....:.| |.|..::
 Frog   788 EGGKCPK---EEDHRAKGLGMENIGGI---FVVLICGLIIAVFVAIME-FVWSTRR 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir10a	NP_001096949.1	Periplasmic_Binding_Protein_Type_2	220..>294	CDD:473866	17/82 (21%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	45/222 (20%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	81/413 (20%)