Protein Alignment CG44422 and Ncs1

DIOPT Version :10

• Sequence 1: NP_572699.2
• Gene: CG44422 / 32063
• FlyBaseID: FBgn0265595
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_062655.1
• Gene: Ncs1 / 14299
• MGIID: 109166
• Length: 190
• Species: Mus musculus
• Alignment Length: 181
• Identity: 83/181 - (45%)
• Similarity: 124/181 - (68%)
• Gaps: 3/181 - (1%)

  Fly   251 ARYRPDSLSALSRATRFTEDEIKRIYRGFKAECPTGVVKEDTFKVIYSQFFPQGANPTLYAHYVF 315
            ::.:|:.:..|:|.|.|||.|:::.|:||..:||:|.:....|:.||.||||.| :||.:|.:||
Mouse     6 SKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFG-DPTKFATFVF 69

  Fly   316 NTLDQDHSGIVSFEDFVQGLSILSRGSVEEKLRWTFSLYDINGDGFITREEMTDIVTAIYELMGR 380
            |..|::..|.:.|.:|:|.||:.|||:::|||||.|.|||::.||:|||.||.|||.|||:::|.
Mouse    70 NVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGN 134

  Fly   381 LPDECPEEEKIKGK-VEQIFQKMDTNRDGVVTLEEFLEACRNDDAISRSMS 430
            .. |.||||....| |::||..||.|.||.:||:||.|..:.|.:|.:::|
Mouse   135 TV-ELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALS 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44422	NP_572699.2	FRQ1	<310..420	CDD:444056	56/110 (51%)
Ncs1	NP_062655.1	FRQ1	22..174	CDD:444056	76/153 (50%)
		Interaction with IL1RAPL1. /evidence=ECO:0000250|UniProtKB:P62166	174..190		3/11 (27%)