Protein Alignment HOXA10 and abd-A

DIOPT Version :10

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 91/315 - (28%)
• Similarity: 124/315 - (39%)
• Gaps: 85/315 - (26%)

Human   133 PPPPPQQQPPPPPQPPQPAPQATSCSFAQNIKEES--SYCLYDSADKCPKVSATAAELAPFPRGP 195
            ||.....|.......|.|:...:| |..:::.:.|  |.....||.....|:|.||
  Fly   190 PPSAGNSQAGDSSCSPSPSASGSS-SLHRSLNDNSPGSASASASASAASSVAAAAA--------- 244

Human   196 PPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGF-DLPPALASG 259
               ..|...||...:|    .|:.|.....:.|..||...:.           || .|.....|.
  Fly   245 ---AAAAAASSSFAIP----TSKMYPYVSNHPSSHGGLSGMA-----------GFTGLEDKSCSR 291

Human   260 SADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKG 324
            ..|.........|.|    |..|...:|..:.|.|::||.       |.:|..:...|||||:..
  Fly   292 YTDTVMNSYQSMSVP----ASASAQFAQFYQHATAAASAV-------SAASAGAIGVDSLGNACT 345

Human   325 ENAAN--------------------WLT------------------AKSG---RKKRCPYTKHQT 348
            :.|:.                    |:|                  ..:|   |:.|..||:.||
  Fly   346 QPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQT 410

Human   349 LELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIREL 403
            |||||||.||.||||.||:||:.::.||:||:|||||||||||||..|  .::|:
  Fly   411 LELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELR--AVKEI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		29/159 (18%)
		Homeodomain	337..393	CDD:459649	38/55 (69%)
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	38/55 (69%)
		Abdominal-A	456..478	CDD:403567	2/10 (20%)