Protein Alignment HOXA10 and Ubx

DIOPT Version :10

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 118/469 - (25%)
• Similarity: 156/469 - (33%)
• Gaps: 213/469 - (45%)

Human     2 SARKGYLL-----PSPNYPTTMSCSESP---------------AANSFLVDSL------------ 34
            :|.:|:.|     |..|:....:..:||               .|.::..|.|
  Fly    38 AAYRGFPLSLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKD 102

Human    35 ISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGG 99
            |.:..|..||||||.||||||.                            ||      :.|:|..
  Fly   103 IWNTGGSNGGGGGGGGGGGGGA----------------------------GG------TGGAGNA 133

Human   100 GGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQATSCSFAQNIK 164
            .||....|:|                             |..|....|.:|
  Fly   134 NGGNAANANG-----------------------------QNNPAGGMPVRP-------------- 155

Human   165 EESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGY--- 226
               |.|..||     :|                 |..|.||.|.||      |...|:|.|.
  Fly   156 ---SACTPDS-----RV-----------------GGYLDTSGGSPV------SHRGGSAGGNVSV 189

Human   227 --GSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGD 289
              |:|..|..|.|.|               ...:|:|..|.              |...|
  Fly   190 SGGNGNAGGVQSGVG---------------VAGAGTAWNAN--------------CTISG----- 220

Human   290 EEAHASSSAAEELSPA---------------PSESSKASPEKD---------SLGNSKGENAA-- 328
              |.|.::||..|..|               |.:.:|:....|         .:|....|:.|
  Fly   221 --AAAQTAAASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGS 283

Human   329 ---NWLTAKSGRKK-RCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRM 389
               :||.....|:: |..||::|||||||||..|.||||.||:|::.::.||:||:|||||||||
  Fly   284 LLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRM 348

Human   390 KLKKMNRENRIREL 403
            ||||  ....|:||
  Fly   349 KLKK--EIQAIKEL 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		10/68 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		29/151 (19%)
		Homeodomain	337..393	CDD:459649	36/56 (64%)
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	35/55 (64%)