Protein Alignment HOXA10 and exex

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 112/501 - (22%)
• Similarity: 143/501 - (28%)
• Gaps: 197/501 - (39%)

Human    66 PPAADLPYGLQSCGLFPTLGGKRNE------AASPGSGGGGGG---------LGPGA------HG 109
            |||.|...|.....|.|     |::      ||||.......|         |.||.      ..
  Fly    50 PPAQDYDQGSNQSTLSP-----RSQITPSPPAASPTHSAATTGSPVSTYTPALSPGGAQDSSQTE 109

Human   110 YGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQ---------------------------------- 140
            .|.|.....|.||......||...||||..:
  Fly   110 SGQSSQMPLLVAPMPVGTGPPHSHPPPPHPRLYVEGFPPPHHVPHPHPALGTYPLPRLPLMLPAN 174

Human   141 PP--------PPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPP 197
            ||        |||..||||....|.|.|                    ..||...|.|....|..
  Fly   175 PPGVPSGAAAPPPVSPQPAANHLSHSGA--------------------TMATTTLLPPAQSQPKK 219

Human   198 DGC---ALGTS---SGVPVP---------------------GYFRLSQAYGTAKGYGSGGGGAQQ 235
            ..|   .|..|   ||.|.|                     .:...|.|...|:...|..||..:
  Fly   220 SFCIDALLAKSQHQSGEPQPIIVDDRLAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISE 284

Human   236 LGA-----------GPFP-----AQPPGRGFDLPPALASGSADAARKERALDS------------ 272
            ..|           .|.|     ::.|.......|.::.|..|..:...||..
  Fly   285 QEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHD 349

Human   273 ------PP-----PPTLACGSGGG-----SQGDEEAHASSSAAEELSPAPSESS----------- 310
                  ||     |......:||.     :||....|.....:.:..|.|...:
  Fly   350 EFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFL 414

Human   311 -------------KASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT 362
                         .|.|....||.:              |:.|..:|..|.|||||:|..|.||:
  Fly   415 ARAGMLHHRIPELAAYPHHAILGKT--------------RRPRTAFTSQQLLELEKQFKQNKYLS 465

Human   363 RERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFN 408
            |.:|.|::..:.|::.||||||||||||.|:..:..:..:..|..|
  Fly   466 RPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKAN 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		29/131 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		28/185 (15%)
		Homeobox	339..392	CDD:278475	28/52 (54%)
exex	NP_648164.1	Homeobox	442..495	CDD:278475	28/52 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910