Protein Alignment HOXA10 and Dbx

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 393
• Identity: 91/393 - (23%)
• Similarity: 122/393 - (31%)
• Gaps: 167/393 - (42%)

Human    15 PTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCG 79
            |.|.|.|.||  .|.:.||..:.|...|.|.|.|.|..|... ..|......|..|      |..
  Fly   274 PQTASSSSSP--GSTISDSDNNHGASTANGNGSGTGNSGQDA-RPHELANSNPDED------SSA 329

Human    80 LFPTLGGKRNEAASPGSGGGGGGLGPGAHGYG-PSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPP 143
            .......|:.:....|:||.||| |.|.||:| |:|              ||  |||||....|.
  Fly   330 SRRLTQDKQQQQQLLGAGGTGGG-GGGGHGHGHPTP--------------PP--PPPPPVIAKPM 377

Human   144 PPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGV 208
            |.:|....|...:.....::   .::|                      |.|
  Fly   378 PSRPTPFLPHTLNHPHLHSL---LAHC----------------------RNP------------- 404

Human   209 PVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSP 273
                             |.|       :||..||. |||:||..
  Fly   405 -----------------YMS-------VGAQVFPL-PPGQGFPW--------------------- 423

Human   274 PPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRK 338
                              ||               |::..|.:                   |..
  Fly   424 ------------------AH---------------STRGKPRR-------------------GMM 436

Human   339 KRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIREL 403
            :|..::..|...|||.|....|:::..|.:::..:.|.|.||||||||||||.    |.::.|||
  Fly   437 RRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKW----RNSKEREL 497

Human   404 TAN 406
            .|:
  Fly   498 LAS 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		24/69 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		16/117 (14%)
		Homeobox	339..392	CDD:278475	22/52 (42%)
Dbx	NP_647677.2	Homeobox	437..490	CDD:278475	22/56 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910